CC170_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC170_HUMAN
• UniProt AC: Q8IYT3
• Protein Name: Coiled-coil domain-containing protein 170
• Gene Name: CCDC170
• Organism: Homo sapiens (Human).
• Sequence Length: 715
• Protein Sequence: MSLDCTSHIALGAASPAPEETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Phosphorylation	HLSEVPVTREQLNHY CHHCCCCCHHHHHHH	23.55	27251275
38	Phosphorylation	TREQLNHYRNVAQNA CHHHHHHHHHHHHHH	11.65	27251275
47	Phosphorylation	NVAQNARSELAATLV HHHHHHHHHHHHHHH	34.25	-
52	Phosphorylation	ARSELAATLVKFECA HHHHHHHHHHHHHHH	26.86	-
72	Phosphorylation	DLRSKMLSKEVSCQE HHHHHHHCCCCCHHH	24.22	27135362
86	Phosphorylation	ELKAEMESYKENNAR HHHHHHHHHHHHCHH	39.95	27135362
87	Phosphorylation	LKAEMESYKENNARK HHHHHHHHHHHCHHH	14.71	28060719
95	Phosphorylation	KENNARKSSLLTSLR HHHCHHHHHHHHHHH	22.21	23312004
96	Phosphorylation	ENNARKSSLLTSLRD HHCHHHHHHHHHHHH	30.36	27966365
99	Phosphorylation	ARKSSLLTSLRDRVQ HHHHHHHHHHHHHHH	30.89	23312004
100	Phosphorylation	RKSSLLTSLRDRVQE HHHHHHHHHHHHHHH	22.75	23312004
122	Phosphorylation	LSTSKIRTEITAHAA HCCHHHHHHHHHHHH	34.90	-
228	Phosphorylation	HEMEAKASRETIMRL HHHHHHHHHHHHHHH	29.91	27251275
275	Sumoylation	EALEREVKIFQERLL HHHHHHHHHHHHHHH	32.81	-
275	Sumoylation	EALEREVKIFQERLL HHHHHHHHHHHHHHH	32.81	-
296	Phosphorylation	DASKQEVSLLKKSSS HHCHHHHHHHHCCHH	27.51	24719451
301	Phosphorylation	EVSLLKKSSSELEKS HHHHHHCCHHHHHHH	37.19	29396449
302	Phosphorylation	VSLLKKSSSELEKSL HHHHHCCHHHHHHHH	36.39	29396449
303	Phosphorylation	SLLKKSSSELEKSLK HHHHCCHHHHHHHHH	53.98	29396449
319	Phosphorylation	SQDAVTTSQSQYFSF CCCCCCCCHHHHCCH	20.61	-
323	Phosphorylation	VTTSQSQYFSFREKI CCCCHHHHCCHHHHH	13.36	-
325	Phosphorylation	TSQSQYFSFREKIAA CCHHHHCCHHHHHHH	20.61	24719451
341	Phosphorylation	LRGRLSMTGSTEDTI HHCCCCCCCCCHHHH	25.30	25599653
343	Phosphorylation	GRLSMTGSTEDTILE CCCCCCCCCHHHHHH	21.32	25599653
347	Phosphorylation	MTGSTEDTILEKIRE CCCCCHHHHHHHHHH	22.64	25599653
357	Phosphorylation	EKIREMDSREESRDR HHHHHCCCHHHHHHH	40.04	-
361	Phosphorylation	EMDSREESRDRMVSQ HCCCHHHHHHHHHHH	34.43	-
481	Phosphorylation	NAVIENKTIAHNLQR CCEECCHHHHHHHHH	34.67	-
499	Phosphorylation	TQKERLESKELHMSL HHHHHHHHHHHHHHH	35.70	-
522	Phosphorylation	EEEKQARTALVVERD HHHHHHCCEEEEECC	27.62	-
573	Phosphorylation	TNELKIKTLEQTKAI CCCCEEHHHHHHHHH	38.71	29396449
603	Phosphorylation	KAEKKLMSVKSELDT HHHHHHHHHHHHHCC	36.51	24719451
630	Phosphorylation	RNMIEVVTSEMKTLK HHHHHHHHHHHHHHH	24.93	-
631	Phosphorylation	NMIEVVTSEMKTLKK HHHHHHHHHHHHHHH	24.88	-
639	Phosphorylation	EMKTLKKSLEEAEKR HHHHHHHHHHHHHHH	39.15	29396449
658	Phosphorylation	ADFREVVSQMLGLNV HHHHHHHHHHHCCCC	18.30	29978859
666	Phosphorylation	QMLGLNVTSLALPDY HHHCCCCHHCCCCCH	19.56	29978859
667	Phosphorylation	MLGLNVTSLALPDYE HHCCCCHHCCCCCHH	13.83	29978859
673	Phosphorylation	TSLALPDYEIIKCLE HHCCCCCHHHHHHHH	13.69	29978859

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC170_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC170_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC170_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CC170_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.