CC157_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC157_HUMAN
• UniProt AC: Q569K6
• Protein Name: Coiled-coil domain-containing protein 157
• Gene Name: CCDC157
• Organism: Homo sapiens (Human).
• Sequence Length: 752
• Protein Sequence: MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCMSYLENLGSEQMMPPAQAAGPCMSVGLTVRRFWDSLLRLGTLHQQPLPQKGANQRETPTSKPTTKGEPARSPEYLTTKLIKPSSPVLGLPQTCQEPESIPVRASLQFPATTFKNTRSVHSQTIETALVPCDACASVQGSLQKVGKVVISLCQSQNLPSSLGQFQQLVQDSMGLRPLPAATVGRWAAEQRKDLTRLSKHVEALRAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAEEDEQCLSEWEHDKQQLLTETSDLKTKMATLERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQLQSEREQGQCQLRAQQELLQSLQREKQGLEQATTDLRLTILELERELEELKERERLLVAFPDLHRPTETQIHGGRSSSVESQITCPTDSGNVTDHMERQVQSNDIRIRVLQEENGRLQSMLSKIREVAQQGGLKLIPQDRLWSPSSKGTQGATPPVQAKSTSPGPLGRQHLPSSRTGRTLLGQPCTSPPRQPCTSPPRQPCTSPPRQPCTSPSRQPCSQPSKSLLEGVTHLDTCTQNPIKVLVRLRKRLSPGRGQASSAHQPQERPM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MAHLLGSQACMESL -CCCHHHHHHHHHHH	17.99	25332170
13	Phosphorylation	GSQACMESLRTDLTD HHHHHHHHHHHCCHH	9.03	24043423
126	Phosphorylation	TVRRFWDSLLRLGTL HHHHHHHHHHHHCCC	21.65	24719451
162	Phosphorylation	TKGEPARSPEYLTTK CCCCCCCCHHHHHCC	24.96	27251275
165	Phosphorylation	EPARSPEYLTTKLIK CCCCCHHHHHCCCCC	16.84	27251275
167	Phosphorylation	ARSPEYLTTKLIKPS CCCHHHHHCCCCCCC	22.45	27251275
168	Phosphorylation	RSPEYLTTKLIKPSS CCHHHHHCCCCCCCC	22.66	27251275
174	Phosphorylation	TTKLIKPSSPVLGLP HCCCCCCCCCCCCCC	42.12	28348404
175	Phosphorylation	TKLIKPSSPVLGLPQ CCCCCCCCCCCCCCC	27.79	28348404
284	Phosphorylation	AEQRKDLTRLSKHVE HHHHHHHHHHHHHHH	39.43	23403867
287	Phosphorylation	RKDLTRLSKHVEALR HHHHHHHHHHHHHHH	19.88	23403867
370	Phosphorylation	ELKQQRESTQAVEAK HHHHHHHHHHHHHHH	28.19	25884760
506	Phosphorylation	AQQELLQSLQREKQG HHHHHHHHHHHHHHH	26.83	-
604	Phosphorylation	EENGRLQSMLSKIRE HHCCHHHHHHHHHHH	26.70	23403867
607	Phosphorylation	GRLQSMLSKIREVAQ CHHHHHHHHHHHHHH	19.86	24260401
630	Phosphorylation	QDRLWSPSSKGTQGA CCCCCCCCCCCCCCC	38.88	-
631	Phosphorylation	DRLWSPSSKGTQGAT CCCCCCCCCCCCCCC	38.19	-
634	Phosphorylation	WSPSSKGTQGATPPV CCCCCCCCCCCCCCC	27.80	23532336
645	Phosphorylation	TPPVQAKSTSPGPLG CCCCCCCCCCCCCCC	36.81	-
647	Phosphorylation	PVQAKSTSPGPLGRQ CCCCCCCCCCCCCCC	34.64	27966365
688	Phosphorylation	PPRQPCTSPPRQPCT CCCCCCCCCCCCCCC	39.36	25690035
703	Phosphorylation	SPSRQPCSQPSKSLL CCCCCCCCCCCHHHH	52.38	-
708	Phosphorylation	PCSQPSKSLLEGVTH CCCCCCHHHHCCCCC	42.39	-
735	Phosphorylation	VRLRKRLSPGRGQAS HHHHHHCCCCCCCCC	29.37	24719451
743	Phosphorylation	PGRGQASSAHQPQER CCCCCCCCCCCCCCC	32.55	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC157_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC157_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC157_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CC157_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.