CC110_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC110_MOUSE
• UniProt AC: Q3V125
• Protein Name: Coiled-coil domain-containing protein 110
• Gene Name: Ccdc110
• Organism: Mus musculus (Mouse).
• Sequence Length: 848
• Subcellular Localization: Nucleus.
• Protein Sequence: MSPGYLPAPKAVLGSVPEKHLAEEDEVDSILLSASKILNSSEGVKESGGNEPEYGCASEPENQIQPQSALKVLQHQLESFQALRMQTLQNVSMVQSEISEILNKSIVEVETPQFNSEKSLVFSMHPEKDLPNETQEEIPSTKTLHSMGETFSSNSDTGLPQGTDIPPQIQVKDMLALQGLRTTADNSPPKKAMNTSEQPSATKSFSLYQFLPQGPQTAVPQAAPVILDKSTITTPFPKHGFCANLDDICHSIKHMKEELQKSHDKELALTSELHTFQADASTQGHHKHEPFPMHSSKLNFIQQENMEGNLSEDMKSKRISELEALVSKLLPLRDTVSKLHVNFCRKCKKLSKSEVYRGKKNEKNKDIPITSKNIMDLKFHSRAPRYTLSVLDLGKHKIKDKEGQAFIVSQGPATLENEKLPKGKFIPEQCVPKQSVAKIHYLQNYLKESLQNQKKMTELENENLALKTKMKPLVFTAQSLIQKVEAHEKQLKSLAEEKSALQSKLSKAEEENKDCLRELKKIVSTYNVLGGQHKMLEEKNSQLSLEKQQMLETIDHLKSKEHKSQSDMAVLQNENSRMNIEIEAMKTSMLLVQDEREMLEKETYQLLKDKSTLESDLKESKLEILQLKEKERLIKAEQESLLHSLDTAKAEKLSLEATLQESTSTRQKLERKLVDIQAYQSAAEEKFLKEIKSAKSETSIYKNNLAEISKECEILSKMVMEIKADNQILKEELKKHSQENTKFENSISRLTEDKILLENYVRSIENEKDTLEFEMRNLQRDYLSLSDKVSSQNNSASKSTYISRREKLYFDNYDAYEDASSLRNRPVASDLKGIPHKLYQRLPSKICK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSPGYLPAP ------CCCCCCCCC	27.34	26643407
5	Phosphorylation	---MSPGYLPAPKAV ---CCCCCCCCCHHH	16.94	26643407
15	Phosphorylation	APKAVLGSVPEKHLA CCHHHCCCCCHHHCC	30.27	26643407
29	Phosphorylation	AEEDEVDSILLSASK CCHHHHHHHHHHHHH	21.95	26643407
33	Phosphorylation	EVDSILLSASKILNS HHHHHHHHHHHHHHC	27.35	26643407
35	Phosphorylation	DSILLSASKILNSSE HHHHHHHHHHHHCCC	19.49	26643407
105	Phosphorylation	ISEILNKSIVEVETP HHHHHCCCCEEEECC	30.69	22817900
111	Phosphorylation	KSIVEVETPQFNSEK CCCEEEECCCCCCCC	27.80	22817900
365	Succinylation	GKKNEKNKDIPITSK CCCCCCCCCCCCCCC	69.01	23954790
547	Acetylation	NSQLSLEKQQMLETI HCCCCHHHHHHHHHH	51.64	15630151
558	Acetylation	LETIDHLKSKEHKSQ HHHHHHHHHCCCCCH	56.94	15630159
620	Phosphorylation	LESDLKESKLEILQL HHHHHHHHHHHHHHH	40.74	22817900
640	Phosphorylation	LIKAEQESLLHSLDT HHHHHHHHHHHHHHH	35.61	20139300
644	Phosphorylation	EQESLLHSLDTAKAE HHHHHHHHHHHHHHH	28.10	20139300
647	Phosphorylation	SLLHSLDTAKAEKLS HHHHHHHHHHHHHHC	35.04	20139300
717	Acetylation	KECEILSKMVMEIKA HHHHHHHHHHHHHHH	31.88	15612513
723	Acetylation	SKMVMEIKADNQILK HHHHHHHHHCCHHHH	36.06	15611767

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC110_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC110_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC110_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CC110_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.