CC110_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC110_HUMAN
• UniProt AC: Q8TBZ0
• Protein Name: Coiled-coil domain-containing protein 110
• Gene Name: CCDC110
• Organism: Homo sapiens (Human).
• Sequence Length: 833
• Subcellular Localization: Nucleus .
• Protein Sequence: MSPEKQHREEDEVDSVLLSASKILNSSEGVKESGCSDTEYGCIAESENQIQPQSALKVLQQQLESFQALRMQTLQNVSMVQSEISEILNKSIIEVENPQFSSEKNLVFGTRIEKDLPTENQEENLSMEKSHHFEDSKTLHSVEEKLSGDSVNSLPQSVNVPSQIHSEDTLTLRTSTDNLSSNIIIHPSENSDILKNYNNFYRFLPTAPPNVMSQADTVILDKSKITVPFLKHGFCENLDDICHSIKQMKEELQKSHDGEVALTNELQTLQTDPDVHRNGKYDMSPIHQDKMNFIKEENLDGNLNEDIKSKRISELEALVKKLLPFRETVSKFHVHFCRKCKKLSKSEMHRGKKNEKNNKEIPITGKNITDLKFHSRVPRYTLSFLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKTNILLIQDEKEMLEKKTHQLLKEKSSLGNELKESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIENIQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEMLSKMVMETKTDNQILKEELKKHSQENIKFENSISRLTEDKILLENYVRSIENERDTLEFEMRHLQREYLSLSDKICNQHNDPSKTTYISRREKFHFDNYTHEDTSSPQSRPLASDLKGYFKVKDRTLKHH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	REEDEVDSVLLSASK CCHHHHHHHHHHHHH	21.60	30631047
19	Phosphorylation	EVDSVLLSASKILNS HHHHHHHHHHHHHCC	26.74	23312004
21	Phosphorylation	DSVLLSASKILNSSE HHHHHHHHHHHCCCC	19.49	30631047
73	Phosphorylation	FQALRMQTLQNVSMV HHHHHHHHHHHHHHH	22.44	24043423
78	Phosphorylation	MQTLQNVSMVQSEIS HHHHHHHHHHHHHHH	22.30	24043423
82	Phosphorylation	QNVSMVQSEISEILN HHHHHHHHHHHHHHH	26.03	24043423
89 (in isoform 2)	Phosphorylation	-	41.51	29116813
101	Phosphorylation	EVENPQFSSEKNLVF EECCCCCCCCCCEEE	32.13	28787133
102	Phosphorylation	VENPQFSSEKNLVFG ECCCCCCCCCCEEEE	54.61	28787133
118	Phosphorylation	RIEKDLPTENQEENL EECCCCCCCCHHHHC	55.66	-
126	Phosphorylation	ENQEENLSMEKSHHF CCHHHHCCHHHHHCC	36.16	-
313	O-linked_Glycosylation	DIKSKRISELEALVK HHHHHHHHHHHHHHH	39.91	30379171
344	Phosphorylation	CRKCKKLSKSEMHRG HHHCCCCCHHHHHCC	42.91	23403867
346	Phosphorylation	KCKKLSKSEMHRGKK HCCCCCHHHHHCCCC	36.45	23403867
388	O-linked_Glycosylation	TLSFLDQTKHEMKDK HHHHHHHCCHHCCCC	33.75	30379171
488	Phosphorylation	KNLVEEKSTIQSKLS HHHHHHHHHHHHHHH	33.74	21712546
489	Phosphorylation	NLVEEKSTIQSKLSK HHHHHHHHHHHHHHC	33.82	21712546
609	Phosphorylation	LGNELKESQLEIIQL CCHHHHHHHHHHHHH	38.18	-
651	Phosphorylation	LETTLQESTAARQIM HHHHHHHHHHHHHHH	15.47	24719451
705	Phosphorylation	GKECEMLSKMVMETK HHHHHHHHHHHHHCC	19.86	30622161
771	Phosphorylation	MRHLQREYLSLSDKI HHHHHHHHHHHHHHH	12.09	25690035
775	Phosphorylation	QREYLSLSDKICNQH HHHHHHHHHHHHHHC	33.22	25690035
803	Phosphorylation	KFHFDNYTHEDTSSP HCCCCCCCCCCCCCC	25.66	18669648
807	Phosphorylation	DNYTHEDTSSPQSRP CCCCCCCCCCCCCCC	28.28	18669648
808	Phosphorylation	NYTHEDTSSPQSRPL CCCCCCCCCCCCCCC	52.95	18669648
809	Phosphorylation	YTHEDTSSPQSRPLA CCCCCCCCCCCCCCH	29.11	18669648
817	Phosphorylation	PQSRPLASDLKGYFK CCCCCCHHHHCCEEE	51.68	-
820	Acetylation	RPLASDLKGYFKVKD CCCHHHHCCEEEECC	57.46	20167786

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC110_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC110_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC110_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
XDH_HUMAN	XDH	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.