CBR3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CBR3_MOUSE
• UniProt AC: Q8K354
• Protein Name: Carbonyl reductase [NADPH] 3
• Gene Name: Cbr3
• Organism: Mus musculus (Mouse).
• Sequence Length: 277
• Subcellular Localization: Cytoplasm.
• Protein Description: Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro)..
• Protein Sequence: MSSCSRVALVTGANKGIGFAITRDLCRKFSGDVVLTARDEARGRAAVQQLQAEGLSPRFHQLDIDDPQSIRALRDFLRKEYGGLNVLVNNAGIAFRMDDPTPFDIQAEVTLKTNFFATRNVCTELLPIMKPHGRVVNISSLQGLKALENCREDLQEKFRCDTLTEVDLVDLMKKFVEDTKNEVHEREGWPDSAYGVSKLGVTVLTRILARQLDEKRKADRILLNACCPGWVKTDMARDQGSRTVEEGAETPVYLALLPPDATEPHGQLVRDKVVQTW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSSCSRVAL ------CCCCCEEEE	39.80	-
2	Phosphorylation	------MSSCSRVAL ------CCCCCEEEE	39.80	-
30	Phosphorylation	RDLCRKFSGDVVLTA HHHHHHCCCCEEEEE	36.80	21082442
56	Phosphorylation	QLQAEGLSPRFHQLD HHHHCCCCCCCCCCC	25.53	21183079
162	Phosphorylation	QEKFRCDTLTEVDLV HHHHCCCCCCCCHHH	38.92	26643407
164	Phosphorylation	KFRCDTLTEVDLVDL HHCCCCCCCCHHHHH	35.73	26643407
253	Phosphorylation	EGAETPVYLALLPPD CCCCCCEEEEECCCC	6.35	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CBR3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CBR3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CBR3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CBR3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.