CBPA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CBPA1_HUMAN
• UniProt AC: P15085
• Protein Name: Carboxypeptidase A1
• Gene Name: CPA1
• Organism: Homo sapiens (Human).
• Sequence Length: 419
• Subcellular Localization: Secreted.
• Protein Description: Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro..
• Protein Sequence: MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
152	Phosphorylation	KIQIGNTYEGRPIYV EEEECCCCCCCEEEE	22.01	-
158	Phosphorylation	TYEGRPIYVLKFSTG CCCCCEEEEEEECCC	11.47	-
272	Phosphorylation	GASSNPCSETYHGKF CCCCCCCCCCCCCCC	33.94	-
274	Phosphorylation	SSNPCSETYHGKFAN CCCCCCCCCCCCCCC	12.43	-
288	Phosphorylation	NSEVEVKSIVDFVKD CCEEEEEHHHHHHHH	32.78	29083192
338	Phosphorylation	QLSKAAVTALASLYG HHHHHHHHHHHHHHC	15.95	25022875
342	Phosphorylation	AAVTALASLYGTKFN HHHHHHHHHHCCCCC	23.99	25022875
344	Phosphorylation	VTALASLYGTKFNYG HHHHHHHHCCCCCHH	21.91	25022875
346	Phosphorylation	ALASLYGTKFNYGSI HHHHHHCCCCCHHHH	20.93	21712546
350	Phosphorylation	LYGTKFNYGSIIKAI HHCCCCCHHHHHHHH	18.51	25022875
352	Phosphorylation	GTKFNYGSIIKAIYQ CCCCCHHHHHHHHHH	15.69	21712546
399	Phosphorylation	PASQIIPTAKETWLA EHHHCCCCHHHHHHH	39.70	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CBPA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CBPA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CBPA1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CBPA1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.