CBF12_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CBF12_SCHPO
• UniProt AC: O74412
• Protein Name: Transcription factor cbf12
• Gene Name: cbf12
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 963
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor which function may be to trigger the increase of adhesion at stationary phase, possibly by counteracting or replacing cbf11 at the respective promoters. May also play a cbf11-antagonistic role in the regulation of a number of other important processes such as extracellular material production, colony morphogenesis, ploidy maintenance, or meiosis..
• Protein Sequence: MSPNVQKRPSSEDIKTQEFYDSTRNIRRVATAIGSINANLESPQLYSLAKSTSLQEPVRIYGDSVSPAISSSKAHSTSSVSPYYSEKNESQALNADGTAFANPSFHSFGLPQEDSQDNTQTYSTPYTTMNPSNEMHPYPPATFENNYSVLPDHSSQPNAYSFTGSNILPTQSPSLNQMQDYQNLQQNGSSNTTIPSFSSQHDLSQGLTHQPVPNHDEYAFSYPYELQRKPLIPAHPVPSFRPTSALKVNMNSNVPSSDSVRNSSPNQYYASTSKQSIPSQSQNLQPPQKASVLGTVNNYRQYQNSFISLNDYQAAQSNISSPSSRFPTPYSPSVPFGTYQEKEKSYSQDHAELSYYQQSPSMMPPYDRSSVYFQQPLSRTDVPNQSFQQYPTTVDGGSMIPNLYPTSAEQMGLYPQDSQNKDTYPKSLVNRPSSAVCEPARNDSIPMMVYSQPVTIEQRIQYVLSNCHCLSAFYLCMPSLCQKSYGTERRYLCPPIVLYLLGTTWLNNVTDNLKISAQTLEDKDNPKFAKNIFYYNADGALISPETDIAKSTYQLTNYNENTNFDSFPVWGNALLKTIYYTGQGKNDGFGRSTFLQLSVQSKTKYFKLENLRLGVISKPSQKRALMKVSDMSIRHGDCVCLFNRYRAQHNNALFLGTSNVQRAISKVSLNMKYNSNYFPTTDAPNDAENEGAGLAMANNLWEPFYIFSVDELNKGNNSNPSDSRSKVLCSNMVIILVSKITGVQSPPLILKKHDNWKVSLSSRAPSEAINCLSKLAFQCHETKRFLYIDEKQSSEISFTSGELEYSDPNDPTKATHSVLPWSAMWSIISTQSVRTMFYNEPIHQNAFHVVPSMPFVKFIRLDENSMFHIYGTGFANDVQIWMAYTRCEVKSINAFKPDTTLPPDIISDSRFSSRVYACTANLIELICEIPVCMFEPTVELSPILLFQYETLFHSGYKWPLESH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	PNVQKRPSSEDIKTQ CCCCCCCCHHHCCHH	50.85	21712547
11	Phosphorylation	NVQKRPSSEDIKTQE CCCCCCCHHHCCHHH	41.81	25720772
53	Phosphorylation	YSLAKSTSLQEPVRI HHHHHCCCCCCCEEE	34.84	27738172
66	Phosphorylation	RIYGDSVSPAISSSK EECCCCCCHHHCCCC	16.74	29996109
76	Phosphorylation	ISSSKAHSTSSVSPY HCCCCCCCCCCCCCC	34.54	21712547
78	Phosphorylation	SSKAHSTSSVSPYYS CCCCCCCCCCCCCCC	31.58	21712547
79	Phosphorylation	SKAHSTSSVSPYYSE CCCCCCCCCCCCCCC	27.06	21712547
81	Phosphorylation	AHSTSSVSPYYSEKN CCCCCCCCCCCCCCC	14.77	21712547
263	Phosphorylation	SSDSVRNSSPNQYYA CCHHCCCCCCCCEEE	36.29	21712547
264	Phosphorylation	SDSVRNSSPNQYYAS CHHCCCCCCCCEEEC	31.27	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CBF12_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CBF12_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CBF12_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GSF2_SCHPO	gsf2	genetic	23236291

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.