CAYP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CAYP1_HUMAN
• UniProt AC: Q13938
• Protein Name: Calcyphosin
• Gene Name: CAPS
• Organism: Homo sapiens (Human).
• Sequence Length: 189
• Subcellular Localization: Cytoplasm.
• Protein Description: Calcium-binding protein. May play a role in cellular signaling events (Potential)..
• Protein Sequence: MDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	QCLSRGASGIQGLAR HHHHCCCCHHHHHHH	38.97	20886841
38	Phosphorylation	RQLDRDGSRSLDADE HHHCCCCCCCCCHHH	24.00	22617229
40	Phosphorylation	LDRDGSRSLDADEFR HCCCCCCCCCHHHHH	32.09	27966365
74	Phosphorylation	RKWDRNGSGTLDLEE CCCCCCCCCCCCHHH	31.96	27966365
107	Phosphorylation	AAFAKLDRSGDGVVT HHHHHCCCCCCCEEE	53.64	27251275
108	Phosphorylation	AFAKLDRSGDGVVTV HHHHCCCCCCCEEEH	40.68	28348404
126	Phosphorylation	RGVYSGRAHPKVRSG CCCCCCCCCCCCCCC	27.19	27251275
132	Phosphorylation	RAHPKVRSGEWTEDE CCCCCCCCCCCCHHH	44.01	28348404
136	Phosphorylation	KVRSGEWTEDEVLRR CCCCCCCCHHHHHHH	29.29	-
160	Phosphorylation	KDGQVTLAEFQDYYS CCCCEEEEEHHHHHC	13.24	27251275
194	Phosphorylation	WQL------------ HCC------------		27251275
218	Phosphorylation	------------------------------------ ------------------------------------		27251275
222	Phosphorylation	---------------------------------------- ----------------------------------------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
126	S	Phosphorylation	Kinase	PKA	-	Uniprot

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CAYP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CAYP1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CAYP1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.