dbPTM

CARTF_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CARTF_MOUSE
UniProt AC	Q8VHI4
Protein Name	Calcium-responsive transcription factor
Gene Name	Carf
Organism	Mus musculus (Mouse).
Sequence Length	689
Subcellular Localization	Nucleus .
Protein Description	Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence (By similarity)..
Protein Sequence	MEQRHSLAGNCDDGEKSEREAQGFEHRTCMDSGDPSFGQNDPPTILPITAPKTYDSLTSQDMPETLTDTQALHEEQFHLLDQNGQPIQYDLQSLGNSTAQMTGMEQVAIPQEPFADEHSPQDISEEKPTGVRADVLEDSTSNYGLRSPASLVLPKKAGARLVEEPLLAPLQPLSCNTPMWACRLRSCEKIGDSYRGYCVSETELESVLTFHKQQTQTVWGTRQSPSPAKPATRLMWKSQYVPYDGIPFVNAGSRAVVMECQYGPRRKGFQLKKISEQESRSCHLYKATCPARIYIKKVQKFPEYRVPTDPQIDRKIIRLEQEKAFTMLKKNLMDAGGVLRWYVQLPTQQAHQYHESETPGVPLSPSPFPMSPLEEEEAIVRDENCALPSRLHPQVAHKIQELVSQGVGQVYAVRKQLRKFVERELFKPDEIPERHNLSYFPTVNDIKNHIHEVQKSLRTGDVVYNSEIIPATLQWTTDSGNILRETVTVTFAEGNLLGEPIPSKMGTSQTQTAVSPEPLSSFPPKIFTHFQALKLQPRLSSPDGSQALVSVDSHASSSPPGLVDTVGNAEVDNHSVLLGQSQNPGTDTCLTQDNSTSSSTGHLPESVPNPVAEDQLLEGEDVEDAGNPEGSVNRTLLGDVQTVPIQIIDSRPVLVEESLSKNQVKQETNEPTLSTEAKTFLDCKKISAT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
147	Phosphorylation	TSNYGLRSPASLVLP CCCCCCCCCCCEECC	25338131
197	Phosphorylation	IGDSYRGYCVSETEL CCCCCCCEECCHHHH	20139300
206	Phosphorylation	VSETELESVLTFHKQ CCHHHHHHHEEEECC	20139300
209	Phosphorylation	TELESVLTFHKQQTQ HHHHHHEEEECCCCE	20139300

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CARTF_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CARTF_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CARTF_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CARTF_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CARTF_MOUSE

Related Literatures of Post-Translational Modification