CAP1_RAT - dbPTM
CAP1_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CAP1_RAT
UniProt AC Q08163
Protein Name Adenylyl cyclase-associated protein 1
Gene Name Cap1
Organism Rattus norvegicus (Rat).
Sequence Length 474
Subcellular Localization Cell membrane
Peripheral membrane protein.
Protein Description Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity..
Protein Sequence MADMQNLVERLERAVGRLEAVSHTSDMHCGYGDSPSKGAVPYVQAFDSLLANPVAEYLKMSKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAGNKLSDLLAPISEQIQEVITFREKNRGSKFFNHLSAVSESIQALGWVALAAKPGPFVKEMNDAAMFYTNRVLKEYRDVDKKHVDWVRAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSVGSGPPPPPPGPPPPPVPTSSGSDDSASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKPATKKEPALLELEGKKWRVENQENVSNLVIDDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSRDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MADMQNLVE
------CHHHHHHHH		22.45-
31PhosphorylationTSDMHCGYGDSPSKG
CCCCCCCCCCCCCCC		24.1327097102
34PhosphorylationMHCGYGDSPSKGAVP
CCCCCCCCCCCCCCC		27.0630411139
36PhosphorylationCGYGDSPSKGAVPYV
CCCCCCCCCCCCCHH		47.9027097102
62AcetylationAEYLKMSKEIGGDVQ
HHHHHHHHHHCCCHH		50.2622902405
70AcetylationEIGGDVQKHAEMVHT
HHCCCHHHHHHHHHH		44.6322902405
80AcetylationEMVHTGLKLERALLV
HHHHHCCHHHHHHHH		50.0422902405
92S-nitrosylationLLVTASQCQQPAGNK
HHHHHHHCCCCCCCH		3.6222178444
92S-nitrosocysteineLLVTASQCQQPAGNK
HHHHHHHCCCCCCCH		3.62-
169AcetylationFYTNRVLKEYRDVDK
HHHHHHHHHHHCCCH		50.2522902405
176AcetylationKEYRDVDKKHVDWVR
HHHHCCCHHHHHHHH		44.6322902405
177AcetylationEYRDVDKKHVDWVRA
HHHCCCHHHHHHHHH		44.3822902405
208AcetylationTTGLAWSKTGPVAKE
HCCCCCCCCCCCHHH		46.9622902405
227PhosphorylationPSGPSVGSGPPPPPP
CCCCCCCCCCCCCCC		46.0725575281
243PhosphorylationPPPPPVPTSSGSDDS
CCCCCCCCCCCCCCH		35.4425575281
244PhosphorylationPPPPVPTSSGSDDSA
CCCCCCCCCCCCCHH		26.9928689409
245PhosphorylationPPPVPTSSGSDDSAS
CCCCCCCCCCCCHHH		44.8128689409
247PhosphorylationPVPTSSGSDDSASRS
CCCCCCCCCCHHHHH		39.9428689409
250PhosphorylationTSSGSDDSASRSALF
CCCCCCCHHHHHHHH		32.8928689409
252PhosphorylationSGSDDSASRSALFAQ
CCCCCHHHHHHHHHH		30.6228689409
265PhosphorylationAQINQGESITHALKH
HHHHHCCCHHHHHHH		39.3428432305
267PhosphorylationINQGESITHALKHVS
HHHCCCHHHHHHHCC		15.4628432305
286MethylationTHKNPALKAQSGPVR
HCCCCCHHCCCCCCC		46.62-
289PhosphorylationNPALKAQSGPVRSGP
CCCHHCCCCCCCCCC		50.34-
294PhosphorylationAQSGPVRSGPKPFSA
CCCCCCCCCCCCCCC		60.7323984901
297AcetylationGPVRSGPKPFSAPKP
CCCCCCCCCCCCCCC		63.3222902405
300PhosphorylationRSGPKPFSAPKPQTS
CCCCCCCCCCCCCCC		52.7923984901
306PhosphorylationFSAPKPQTSPSPKPA
CCCCCCCCCCCCCCC		51.6527097102
307PhosphorylationSAPKPQTSPSPKPAT
CCCCCCCCCCCCCCC		20.3827097102
309PhosphorylationPKPQTSPSPKPATKK
CCCCCCCCCCCCCCC		45.3727097102
314PhosphorylationSPSPKPATKKEPALL
CCCCCCCCCCCCCEE		51.6927097102
316SuccinylationSPKPATKKEPALLEL
CCCCCCCCCCCEEEE		65.6526843850
326AcetylationALLELEGKKWRVENQ
CEEEECCCEEEECCC		39.5222902405
347AcetylationVIDDTELKQVAYIYK
ECCHHHHHHHHHHHH		36.1722902405
423PhosphorylationHAYLSKNSLDCEIVS
EEEECCCCCCCEEEE		29.3527097102
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CAP1_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CAP1_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CAP1_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CAP1_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CAP1_RAT

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Related Literatures of Post-Translational Modification

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