CAMP3_MOUSE - dbPTM
CAMP3_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CAMP3_MOUSE
UniProt AC Q80VC9
Protein Name Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305}
Gene Name Camsap3 {ECO:0000312|MGI:MGI:1916947}
Organism Mus musculus (Mouse).
Sequence Length 1252
Subcellular Localization Cytoplasm, cytoskeleton . Cell junction, adherens junction . Cytoplasm . Scattered in the cytoplasm, associated with the minus-end of microtubules and also detected at the centrosomes (PubMed:24706919, PubMed:26715742). Decorates the minus-end of mic
Protein Description Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. [PubMed: 23169647]
Protein Sequence MVEAAPAGSGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPFYTDQYAQEHVKPPVTRLLLSAELYCRAWRQALPQLEPSPSPSALLALLARRGTVPSLPEHPVREADLKHQPILMGAHLAVIDALMVAFSFEWTKTLPGPLALSSLEHKLLFWVDTTVRRLQEKTEQEAAQRASPAAPLDGASPAQPSIRYRKDRAIARRAPCFPNVTTLQDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVADSLYNLQLVQDFCASHLPRGCPLSLEDLLYVPPPLKVNLVVLLAEMYMCFEVLKPDFVQAKDLPDGHAVSPRNTETVPSQNNSGSSSPVFNFRHPLLSPGGPQSPLRGSTGSLKSSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPVSTSSRNSAQPAPESGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGLSKPPLSPYPPEGASKPLSDRLNKAPIYISHPENPSKSSPCSTGEILKPPPPSEGSPKAVASSPAANNSEVKMTSFAERKKQLVKAEAESGLGSPTSTPVAPEALSSEMSELGARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREAAGEAEEEAELGSVPGGERPAGEGQGEPSLRHKSVTFSPDLGPVPPEGLGDYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGPAPPPAAWVIPGPATGPKAASPSPARRAPAARRSPGPGPSPTPRSPKHARPAELKLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLSEGTPPEEPTTKPALIEIPLASLGEPAADEEGDGSPPGAEDSLEEEASSEGEPRSGLGFFYKDEDKPEDEMAQKRASLLERQQRRVEEARRRKQWQEAEKEQKREEAARLAQEAPGLAFTTPVVASAAPVATLAPTTRAMAPAEEEVGPRRGDFTRLEYERRAQLKLMDDLDKVLRPRASGTGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKVYSQSTLSLSTVANEAPNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLYKEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALYTLSGETEELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLWQSKKPTTPKKGGGTPK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
9PhosphorylationVEAAPAGSGPLRRTF
CCCCCCCCCCCCCEE		39.0728507225
15PhosphorylationGSGPLRRTFLVPEIK
CCCCCCCEEECCCCC		18.19-
22UbiquitinationTFLVPEIKSLDQYDF
EEECCCCCCCCCCCH		43.22-
22UbiquitinationTFLVPEIKSLDQYDF
EEECCCCCCCCCCCH		43.2222790023
184PhosphorylationVRRLQEKTEQEAAQR
HHHHHHHHHHHHHHH		41.99-
193PhosphorylationQEAAQRASPAAPLDG
HHHHHHHCCCCCCCC		19.7722817900
193 (in isoform 12)Phosphorylation-19.7729899451
193 (in isoform 14)Phosphorylation-19.7729899451
193 (in isoform 15)Phosphorylation-19.7729899451
193 (in isoform 17)Phosphorylation-19.7729899451
193 (in isoform 3)Phosphorylation-19.7729899451
193 (in isoform 5)Phosphorylation-19.7729899451
193 (in isoform 6)Phosphorylation-19.7729899451
193 (in isoform 8)Phosphorylation-19.7729899451
202 (in isoform 12)Phosphorylation-26.7129899451
202 (in isoform 14)Phosphorylation-26.7129899451
202 (in isoform 15)Phosphorylation-26.7129899451
202 (in isoform 17)Phosphorylation-26.7129899451
202 (in isoform 3)Phosphorylation-26.7129899451
202 (in isoform 5)Phosphorylation-26.7129899451
202 (in isoform 6)Phosphorylation-26.7129899451
202 (in isoform 8)Phosphorylation-26.7129899451
334PhosphorylationLPDGHAVSPRNTETV
CCCCCCCCCCCCCCC		20.9425521595
335PhosphorylationPDGHAVSPRNTETVP
CCCCCCCCCCCCCCC		27.2625521595
335PhosphorylationPDGHAVSPRNTETVP
CCCCCCCCCCCCCCC		27.2625521595
335 (in isoform 10)Phosphorylation-27.2626239621
335 (in isoform 13)Phosphorylation-27.2626239621
338PhosphorylationHAVSPRNTETVPSQN
CCCCCCCCCCCCCCC		34.0229472430
340PhosphorylationVSPRNTETVPSQNNS
CCCCCCCCCCCCCCC		35.3626239621
343PhosphorylationRNTETVPSQNNSGSS
CCCCCCCCCCCCCCC		41.0026239621
346 (in isoform 12)Phosphorylation-39.8626239621
346 (in isoform 15)Phosphorylation-39.8626239621
347PhosphorylationTVPSQNNSGSSSPVF
CCCCCCCCCCCCCCE		47.8321082442
349PhosphorylationPSQNNSGSSSPVFNF
CCCCCCCCCCCCEEC		27.7123527152
350PhosphorylationSQNNSGSSSPVFNFR
CCCCCCCCCCCEECC		42.0323527152
351PhosphorylationQNNSGSSSPVFNFRH
CCCCCCCCCCEECCC		27.1225521595
351 (in isoform 11)Phosphorylation-27.1226239621
351 (in isoform 16)Phosphorylation-27.1226239621
362PhosphorylationNFRHPLLSPGGPQSP
ECCCCCCCCCCCCCC		29.2225521595
362 (in isoform 14)Phosphorylation-29.2226239621
362 (in isoform 17)Phosphorylation-29.2226239621
368PhosphorylationLSPGGPQSPLRGSTG
CCCCCCCCCCCCCCC		29.0925521595
373PhosphorylationPQSPLRGSTGSLKSS
CCCCCCCCCCCCCCC		24.1429899451
374PhosphorylationQSPLRGSTGSLKSSP
CCCCCCCCCCCCCCC		33.3529899451
379PhosphorylationGSTGSLKSSPSMSHM
CCCCCCCCCCCHHHH		53.4229899451
380PhosphorylationSTGSLKSSPSMSHME
CCCCCCCCCCHHHHH		21.2929472430
382PhosphorylationGSLKSSPSMSHMEAL
CCCCCCCCHHHHHHH		34.5629472430
384PhosphorylationLKSSPSMSHMEALGK
CCCCCCHHHHHHHHH		24.8229472430
398PhosphorylationKAWNRQLSRPLSQAV
HHHHHHCCCCHHHHC		24.4226239621
402PhosphorylationRQLSRPLSQAVSFST
HHCCCCHHHHCCCCC		20.8326239621
406PhosphorylationRPLSQAVSFSTPFGL
CCHHHHCCCCCCCCC		19.2526239621
408PhosphorylationLSQAVSFSTPFGLDS
HHHHCCCCCCCCCCC		27.8826239621
409PhosphorylationSQAVSFSTPFGLDSD
HHHCCCCCCCCCCCC		22.1826239621
415PhosphorylationSTPFGLDSDVDVVMG
CCCCCCCCCCCEEEC		44.5726239621
429PhosphorylationGDPVLLRSVSSDSLG
CCCEEEEECCCCCCC		26.7327087446
431PhosphorylationPVLLRSVSSDSLGPP
CEEEEECCCCCCCCC		29.6727087446
432PhosphorylationVLLRSVSSDSLGPPR
EEEEECCCCCCCCCC		29.1226239621
434PhosphorylationLRSVSSDSLGPPRPV
EEECCCCCCCCCCCC		36.8522324799
442PhosphorylationLGPPRPVSTSSRNSA
CCCCCCCCCCCCCCC		25.8423984901
443PhosphorylationGPPRPVSTSSRNSAQ
CCCCCCCCCCCCCCC		30.8423984901
444PhosphorylationPPRPVSTSSRNSAQP
CCCCCCCCCCCCCCC		21.5723984901
445PhosphorylationPRPVSTSSRNSAQPA
CCCCCCCCCCCCCCC		35.2523984901
484PhosphorylationPDGAADGSFYLHSPE
CCCCCCCCEEECCCC		15.9722807455
489PhosphorylationDGSFYLHSPEGLSKP
CCCEEECCCCCCCCC		23.2719060867
528PhosphorylationISHPENPSKSSPCST
EECCCCCCCCCCCCC		57.6722817900
530UbiquitinationHPENPSKSSPCSTGE
CCCCCCCCCCCCCCC		43.8027667366
531PhosphorylationPENPSKSSPCSTGEI
CCCCCCCCCCCCCCC		33.3919060867
534PhosphorylationPSKSSPCSTGEILKP
CCCCCCCCCCCCCCC		42.7122807455
545PhosphorylationILKPPPPSEGSPKAV
CCCCCCCCCCCCCCC		61.4325521595
548PhosphorylationPPPPSEGSPKAVASS
CCCCCCCCCCCCCCC		21.1225521595
554PhosphorylationGSPKAVASSPAANNS
CCCCCCCCCCCCCCC		30.2028066266
555PhosphorylationSPKAVASSPAANNSE
CCCCCCCCCCCCCCC		14.6025521595
561PhosphorylationSSPAANNSEVKMTSF
CCCCCCCCCCCCCHH		43.5028066266
586PhosphorylationEAESGLGSPTSTPVA
HHHCCCCCCCCCCCC		30.0122817900
588PhosphorylationESGLGSPTSTPVAPE
HCCCCCCCCCCCCHH		47.1020415495
589PhosphorylationSGLGSPTSTPVAPEA
CCCCCCCCCCCCHHH		33.8129899451
590PhosphorylationGLGSPTSTPVAPEAL
CCCCCCCCCCCHHHH		25.0220415495
635UbiquitinationKHRQRLGKSAFLQVQ
HHHHHHCCCCEEECC		43.1127667366
636UbiquitinationHRQRLGKSAFLQVQP
HHHHHCCCCEEECCC		23.5827667366
636UbiquitinationHRQRLGKSAFLQVQP
HHHHHCCCCEEECCC		23.5822790023
646UbiquitinationLQVQPREAAGEAEEE
EECCCCCCCCCHHHH		23.2627667366
647UbiquitinationQVQPREAAGEAEEEA
ECCCCCCCCCHHHHH		16.1727667366
651UbiquitinationREAAGEAEEEAELGS
CCCCCCHHHHHHHCC		52.6627667366
652UbiquitinationEAAGEAEEEAELGSV
CCCCCHHHHHHHCCC		70.3427667366
662UbiquitinationELGSVPGGERPAGEG
HHCCCCCCCCCCCCC		22.9727667366
663UbiquitinationLGSVPGGERPAGEGQ
HCCCCCCCCCCCCCC		62.5027667366
679PhosphorylationEPSLRHKSVTFSPDL
CCCCCCCEEEECCCC		21.9229899451
683PhosphorylationRHKSVTFSPDLGPVP
CCCEEEECCCCCCCC		14.2430372032
703UbiquitinationDYNRAVSKLSAALSS
HHHHHHHHHHHHHHH		39.60-
704UbiquitinationYNRAVSKLSAALSSL
HHHHHHHHHHHHHHH		3.0722790023
709PhosphorylationSKLSAALSSLQRDMQ
HHHHHHHHHHHHHHH		25.0322345495
710PhosphorylationKLSAALSSLQRDMQR
HHHHHHHHHHHHHHH		29.3922802335
754PhosphorylationATGPKAASPSPARRA
CCCCCCCCCCHHHCC		30.6727818261
756PhosphorylationGPKAASPSPARRAPA
CCCCCCCCHHHCCCH		28.7929899451
767PhosphorylationRAPAARRSPGPGPSP
CCCHHHCCCCCCCCC		28.7625521595
773PhosphorylationRSPGPGPSPTPRSPK
CCCCCCCCCCCCCCC		47.5225521595
775PhosphorylationPGPGPSPTPRSPKHA
CCCCCCCCCCCCCCC		35.3529899451
778PhosphorylationGPSPTPRSPKHARPA
CCCCCCCCCCCCCCH		39.2326239621
797PhosphorylationAPLTRVLTPPHDVDS
CCCCCCCCCCCCCCC		31.7325177544
812PhosphorylationLPHLRKFSPSQVPVQ
CCHHHCCCCCCCCCC		27.0325521595
814PhosphorylationHLRKFSPSQVPVQTR
HHHCCCCCCCCCCCC		42.4820415495
820PhosphorylationPSQVPVQTRSSILLS
CCCCCCCCCCCEECC		32.5220415495
827PhosphorylationTRSSILLSEGTPPEE
CCCCEECCCCCCCCC		30.4520415495
830PhosphorylationSILLSEGTPPEEPTT
CEECCCCCCCCCCCC		31.4522817900
836PhosphorylationGTPPEEPTTKPALIE
CCCCCCCCCCCCEEE		51.2121082442
861PhosphorylationADEEGDGSPPGAEDS
CCCCCCCCCCCHHHH		32.4419060867
868PhosphorylationSPPGAEDSLEEEASS
CCCCHHHHHHHHHHC		29.2319060867
881PhosphorylationSSEGEPRSGLGFFYK
HCCCCCCCCCCCEEC		49.4322817900
900UbiquitinationPEDEMAQKRASLLER
CHHHHHHHHHHHHHH		40.15-
901UbiquitinationEDEMAQKRASLLERQ
HHHHHHHHHHHHHHH		19.8222790023
903PhosphorylationEMAQKRASLLERQQR
HHHHHHHHHHHHHHH		37.2022324799
1012UbiquitinationASGTGGPGRGGRRAT
CCCCCCCCCCCCCCC		44.1127667366
1019PhosphorylationGRGGRRATRPRSGCC
CCCCCCCCCCCCCCC		39.1229899451
1023PhosphorylationRRATRPRSGCCDDSA
CCCCCCCCCCCCCHH		38.5725521595
1034PhosphorylationDDSALARSPARGLLG
CCHHHHCCHHHHHHH		19.8023527152
1045PhosphorylationGLLGSRLSKVYSQST
HHHHHHHHHHHCCCC		20.9729899451
1048PhosphorylationGSRLSKVYSQSTLSL
HHHHHHHHCCCCCCH		12.5326239621
1049PhosphorylationSRLSKVYSQSTLSLS
HHHHHHHCCCCCCHH		22.2026239621
1051PhosphorylationLSKVYSQSTLSLSTV
HHHHHCCCCCCHHHH		25.9426239621
1052PhosphorylationSKVYSQSTLSLSTVA
HHHHCCCCCCHHHHC		16.8426239621
1054PhosphorylationVYSQSTLSLSTVANE
HHCCCCCCHHHHCCC		21.9926239621
1056PhosphorylationSQSTLSLSTVANEAP
CCCCCCHHHHCCCCC		19.9126239621
1057PhosphorylationQSTLSLSTVANEAPN
CCCCCHHHHCCCCCC		29.0026239621
1072PhosphorylationNLGVKRPTSRAPSPS
CCCCCCCCCCCCCCC		34.5729899451
1073PhosphorylationLGVKRPTSRAPSPSG
CCCCCCCCCCCCCCC		29.1829899451
1077PhosphorylationRPTSRAPSPSGLMSP
CCCCCCCCCCCCCCC		30.6121082442
1079PhosphorylationTSRAPSPSGLMSPSR
CCCCCCCCCCCCCCC		49.2322324799
1083PhosphorylationPSPSGLMSPSRLPGS
CCCCCCCCCCCCCCC		25.4321082442
1085PhosphorylationPSGLMSPSRLPGSRE
CCCCCCCCCCCCCCC		38.8628066266
1090PhosphorylationSPSRLPGSRERDWEN
CCCCCCCCCCCCCCC		29.0922324799
1099PhosphorylationERDWENGSNASSPAS
CCCCCCCCCCCCCCC		40.5829899451
1102PhosphorylationWENGSNASSPASVPE
CCCCCCCCCCCCCCC		40.9029899451
1103PhosphorylationENGSNASSPASVPEY
CCCCCCCCCCCCCCC		23.2929899451
1106PhosphorylationSNASSPASVPEYTGP
CCCCCCCCCCCCCCC		41.4029899451
1117UbiquitinationYTGPRLYKEPSAKSN
CCCCCCCCCCCCCCC		68.6827667366
1118UbiquitinationTGPRLYKEPSAKSNK
CCCCCCCCCCCCCCC		30.8227667366
1128UbiquitinationAKSNKFIIHNALSHC
CCCCCEEEEHHHHHH		2.0027667366
1129UbiquitinationKSNKFIIHNALSHCC
CCCCEEEEHHHHHHH		14.5427667366
1133UbiquitinationFIIHNALSHCCLAGK
EEEEHHHHHHHHHCC		16.4527667366
1133PhosphorylationFIIHNALSHCCLAGK
EEEEHHHHHHHHHCC		16.4529899451
1134UbiquitinationIIHNALSHCCLAGKV
EEEHHHHHHHHHCCC		13.7327667366
1144UbiquitinationLAGKVNEPQKNRILE
HHCCCCHHHHHHHHH		45.2927667366
1145UbiquitinationAGKVNEPQKNRILEE
HCCCCHHHHHHHHHH		49.8627667366
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CAMP3_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CAMP3_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CAMP3_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CAMP3_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CAMP3_MOUSE

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-334, AND MASSSPECTROMETRY.
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations.";
Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.;
Mol. Cell. Proteomics 6:283-293(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1083, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory