dbPTM

CALY_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CALY_MOUSE
UniProt AC	Q9DCA7
Protein Name	Neuron-specific vesicular protein calcyon
Gene Name	Caly
Organism	Mus musculus (Mouse).
Sequence Length	226
Subcellular Localization	Cytoplasmic vesicle membrane Single-pass membrane protein. Cell membrane Single-pass membrane protein.
Protein Description	Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis..
Protein Sequence	MVKLGCSFSGKPGKEAGDQDGAAMDSVPLISPLDVSQLQPSFSDQVVINTQTEYQLTSADQPKKFADLEGQRLACSHSEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTEMPAVWGNNYRTAKEEHKGTTPAAMAVSTAAAAAAAEGTEPSGKSLDTREKEDPQKAEGVPSQPPK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Ubiquitination	SFSGKPGKEAGDQDG CCCCCCCCCCCCCCC	53.57	-
64	Ubiquitination	TSADQPKKFADLEGQ CCCCCCCCHHCCCCC	53.09	27667366
75	Ubiquitination	LEGQRLACSHSEEGR CCCCEEEECCCCCCC	4.44	27667366
86	Phosphorylation	EEGRRLPTARMIAFA CCCCCCCHHHHHHHH	31.33	28059163
113	Phosphorylation	AIWYDQFTCPDGFLL HHHHHHCCCCCCCCH	19.93	28059163
152	Phosphorylation	ILAAIGAYPLSRKHG HHHHHCCCCCHHHCC	10.25	21454597
155	Phosphorylation	AIGAYPLSRKHGTEM HHCCCCCHHHCCCCC	34.48	21454597

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CALY_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CALY_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CALY_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CALY_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CALY_MOUSE

Related Literatures of Post-Translational Modification