dbPTM

CALM2_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CALM2_ARATH
UniProt AC	P0DH97
Protein Name	Calmodulin-2
Gene Name	CAM2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	149
Subcellular Localization	Cytoplasm, cytoskeleton . Cytoplasm . Recruited by IQD1 to microtubules.
Protein Description	Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases..
Protein Sequence	MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIKEADVDGDGQINYEEFVKVMMAK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MADQLTDDQISEF --CCCCCCHHHHHHH	31.71	25368622
11	Phosphorylation	QLTDDQISEFKEAFS CCCHHHHHHHHHHHH	31.20	30589143
18	Phosphorylation	SEFKEAFSLFDKDGD HHHHHHHHHCCCCCC	34.86	30589143
80	Phosphorylation	MARKMKDTDSEEELK HHHHHCCCCCHHHHH	35.59	30291188
82	Phosphorylation	RKMKDTDSEEELKEA HHHCCCCCHHHHHHH	49.34	30291188
102	Phosphorylation	KDQNGFISAAELRHV CCCCCCCCHHHHHHH	21.11	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CALM2_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CALM2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CALM2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
PTR2_ARATH	PTR2	physical	22737156

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CALM2_ARATH

Related Literatures of Post-Translational Modification