dbPTM

CALI_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CALI_MOUSE
UniProt AC	Q8CDE2
Protein Name	Calicin
Gene Name	Ccin
Organism	Mus musculus (Mouse).
Sequence Length	588
Subcellular Localization	Cytoplasm, cytoskeleton, perinuclear theca, calyx. Sperm head cytoskeletal structure tightly associated to the nucleus..
Protein Description	Possible morphogenetic cytoskeletal element in spermiogenic differentiation..
Protein Sequence	MKLEFTEKNYNSFVLQNLNKQRKRKEYWDMALTVDHHVFFAHRNVLAAVSPLVKSLISSNDMKTTDELYITIDPNYLSPATVDQLLDYFYSGKVVISEQNVEELLRGAQYFNTPRLRIHCNDFLIKSIRRVNCLRYLFLAELFELKEVSDLAYSGIRDNFHFWASPEGSMHFMRCPPVIFGRLLRDENLHVLNEDQALSALISWVYFRKEEREKYFKKFFNYINLNAVSNKTLMFASNKLVGLENNSAHATLIESVLMDRKQERPCSLLSYQRKGALLDSVVILGGQKAHGKFNDGVFAYIIQENLWLKLSEMPYRAAALSATAAGRYIYISGGTTEQISGLKTAWRYDMDDNSWTKLPDLPIGLVFHTMVTCGGTVYSVGGSIAPRRYVSNIYRYDERKEAWCLAGKMSIPMDGTAVITKGDRNLYIVTGRCLVKGYISRVGVVDCFDTCTGEVVQCITFPIEFNHRPLLSFHQDNILRVHSHRQSVEINLQKIKANKSTTSVPLLPNSCPLDVSHAICSIGDSKVFVCGGVTTASDVQTKDYTINPNAYLLDQKIGEWQTLACPPEALDCPACCLAKLPCKILQRI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
149	Phosphorylation	LFELKEVSDLAYSGI HHHCCCCHHHHHCCC	28.18	-
169	Phosphorylation	FWASPEGSMHFMRCP EEECCCCCCCEECCC	13.86	-
231	Acetylation	NLNAVSNKTLMFASN CHHHCCCCEEEEECC	35.21	15624075
239	Acetylation	TLMFASNKLVGLENN EEEEECCCEECCCCC	41.89	15624085
280	Phosphorylation	RKGALLDSVVILGGQ HCCCCCCEEEEECCH	20.46	26160508
410	Phosphorylation	WCLAGKMSIPMDGTA EEEEECEECCCCCCE	27.33	28059163
420	Phosphorylation	MDGTAVITKGDRNLY CCCCEEEECCCCCEE	23.52	28059163

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CALI_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CALI_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CALI_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CALI_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CALI_MOUSE

Related Literatures of Post-Translational Modification