CAH1_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CAH1_RAT
• UniProt AC: B0BNN3
• Protein Name: Carbonic anhydrase 1 {ECO:0000250|UniProtKB:P00915}
• Gene Name: Ca1 {ECO:0000250|UniProtKB:P00915}
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 261
• Subcellular Localization: Cytoplasm .
• Protein Description: Reversible hydration of carbon dioxide..
• Protein Sequence: MASADWGYDSKNGPDQWSKLYPIANGNNQSPIDIKTSEAKHDSSLKPVSVSYNPATAKEIVNVGHSFHVVFDDSSNQSVLKGGPLADSYRLTQFHFHWGNSNDHGSEHTVDGAKYSGELHLVHWNSAKYSSAAEAISKADGLAIIGVLMKVGPANPNLQKVLDALSSVKTKGKRAPFTNFDPSSLLPSSLDYWTYFGSLTHPPLHESVTWVICKESISLSPEQLAQLRGLLSSAEGEPAVPVLSNHRPPQPLKGRTVRASF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MASADWGYD ------CCCCCCCCC	17.27	-
40	Acetylation	DIKTSEAKHDSSLKP CCCCCCCCCCCCCCC	43.84	22902405
46	Acetylation	AKHDSSLKPVSVSYN CCCCCCCCCEEEEEC	45.37	22902405
49	Phosphorylation	DSSLKPVSVSYNPAT CCCCCCEEEEECCCC	17.55	22276854
51	Phosphorylation	SLKPVSVSYNPATAK CCCCEEEEECCCCHH	16.22	22276854
52	Phosphorylation	LKPVSVSYNPATAKE CCCEEEEECCCCHHH	24.02	22276854
56	Phosphorylation	SVSYNPATAKEIVNV EEEECCCCHHHHEEC	39.25	22276854
88	Phosphorylation	KGGPLADSYRLTQFH ECCCCCCEEEEEEEE	13.42	30181290
128	Acetylation	LVHWNSAKYSSAAEA EEEECCCCHHHHHHH	45.55	22902405
129	Phosphorylation	VHWNSAKYSSAAEAI EEECCCCHHHHHHHH	13.94	22673903
130	Phosphorylation	HWNSAKYSSAAEAIS EECCCCHHHHHHHHH	16.88	22673903
131	Phosphorylation	WNSAKYSSAAEAISK ECCCCHHHHHHHHHH	28.54	22673903
137	Phosphorylation	SSAAEAISKADGLAI HHHHHHHHHHCCEEE	28.92	22673903
160	Acetylation	PANPNLQKVLDALSS CCCCCHHHHHHHHHC	48.18	22902405
253	Acetylation	HRPPQPLKGRTVRAS CCCCCCCCCCEEEEC	53.69	22902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CAH1_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CAH1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CAH1_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of CAH1_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.