CAF1B_MOUSE - dbPTM
CAF1B_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CAF1B_MOUSE
UniProt AC Q9D0N7
Protein Name Chromatin assembly factor 1 subunit B
Gene Name Chaf1b
Organism Mus musculus (Mouse).
Sequence Length 572
Subcellular Localization Nucleus. DNA replication foci..
Protein Description Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer (By similarity)..
Protein Sequence MKVITCEIAWHNKEPVYSLDFQHGATWKIHRLASAGVDTAVRIWKLERGPDGKAIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKMNDSKEPEQIAFQDEEEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMTSASVDNTVIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIYNTQKKRVAFNISKMLSGQGPEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCMESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVAETEKASEEPSPELVNLPYRMVFAVASEDSVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCTFVTFEKGELGIPLKEKPVLSIRTPDTAKKAKNQTHQGSSPGSRSVEGTPSNRTQDPSSPCTTPSPTTQSPAPSAIKDSPSAIPAGKSPLPQPSEEKTLQPAGQNMKAPQPRRVTLNTLQTWGKTAPRRINLTPLKTDTVPNPQPNSGTAPSTEEVQPEAPGEPPEEPPELKRPRLEEREGDAQNLAPDDSSKTV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
53UbiquitinationLERGPDGKAIVEFLS
EHHCCCHHHHHHHHH		42.17-
67UbiquitinationSNLARHTKAVNVVRF
HHHHHHCCCEEEEEE		44.18-
120PhosphorylationQLNKENWTVVKTLRG
HHCCCCEEEHHHHHH		27.3128725479
172PhosphorylationSIFNEHKSYVQGVTW
EEECCCCHHCCCCCC		32.2322802335
173PhosphorylationIFNEHKSYVQGVTWD
EECCCCHHCCCCCCC		11.1222802335
178PhosphorylationKSYVQGVTWDPLGQY
CHHCCCCCCCCHHHH		30.8622802335
185PhosphorylationTWDPLGQYIATLSCD
CCCCHHHHHHHHCCC		7.2522802335
188PhosphorylationPLGQYIATLSCDRVL
CHHHHHHHHCCCEEE		15.0522802335
211UbiquitinationRVAFNISKMLSGQGP
EEEEEHHHHHCCCCC		39.81-
398PhosphorylationLKEKPVLSIRTPDTA
CCCCCEEEEECCCHH		15.4025159016
401PhosphorylationKPVLSIRTPDTAKKA
CCEEEEECCCHHHHH		24.6825159016
404PhosphorylationLSIRTPDTAKKAKNQ
EEEECCCHHHHHCCC		41.3925159016
412PhosphorylationAKKAKNQTHQGSSPG
HHHHCCCCCCCCCCC		26.0929550500
416PhosphorylationKNQTHQGSSPGSRSV
CCCCCCCCCCCCCCC		27.1325159016
417PhosphorylationNQTHQGSSPGSRSVE
CCCCCCCCCCCCCCC		39.8522802335
420PhosphorylationHQGSSPGSRSVEGTP
CCCCCCCCCCCCCCC		25.4325159016
422PhosphorylationGSSPGSRSVEGTPSN
CCCCCCCCCCCCCCC		26.6422802335
426PhosphorylationGSRSVEGTPSNRTQD
CCCCCCCCCCCCCCC		15.2725159016
428PhosphorylationRSVEGTPSNRTQDPS
CCCCCCCCCCCCCCC		38.4928066266
431PhosphorylationEGTPSNRTQDPSSPC
CCCCCCCCCCCCCCC		41.3925619855
435PhosphorylationSNRTQDPSSPCTTPS
CCCCCCCCCCCCCCC		56.0222942356
436PhosphorylationNRTQDPSSPCTTPSP
CCCCCCCCCCCCCCC		29.4027087446
439PhosphorylationQDPSSPCTTPSPTTQ
CCCCCCCCCCCCCCC		45.1622942356
440PhosphorylationDPSSPCTTPSPTTQS
CCCCCCCCCCCCCCC		28.6122942356
442PhosphorylationSSPCTTPSPTTQSPA
CCCCCCCCCCCCCCC		32.5522942356
444PhosphorylationPCTTPSPTTQSPAPS
CCCCCCCCCCCCCCC		41.6325619855
445PhosphorylationCTTPSPTTQSPAPSA
CCCCCCCCCCCCCCC		30.3625619855
447PhosphorylationTPSPTTQSPAPSAIK
CCCCCCCCCCCCCCC		22.4225619855
451PhosphorylationTTQSPAPSAIKDSPS
CCCCCCCCCCCCCCC		44.7425619855
456PhosphorylationAPSAIKDSPSAIPAG
CCCCCCCCCCCCCCC		18.7623375375
458PhosphorylationSAIKDSPSAIPAGKS
CCCCCCCCCCCCCCC		42.6625619855
465PhosphorylationSAIPAGKSPLPQPSE
CCCCCCCCCCCCCCC		30.6526824392
471PhosphorylationKSPLPQPSEEKTLQP
CCCCCCCCCCCCCCC		53.8125619855
475PhosphorylationPQPSEEKTLQPAGQN
CCCCCCCCCCCCCCC		33.6324719451
492PhosphorylationAPQPRRVTLNTLQTW
CCCCCCEEHHHHHHC		16.6925266776
495PhosphorylationPRRVTLNTLQTWGKT
CCCEEHHHHHHCCCC		24.2925177544
501AcetylationNTLQTWGKTAPRRIN
HHHHHCCCCCCCEEE		32.8322826441
502PhosphorylationTLQTWGKTAPRRINL
HHHHCCCCCCCEEEC		37.65-
510PhosphorylationAPRRINLTPLKTDTV
CCCEEECEECCCCCC		23.3022942356
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CAF1B_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CAF1B_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CAF1B_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CAF1B_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CAF1B_MOUSE

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Related Literatures of Post-Translational Modification

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