| UniProt ID | CADM3_RAT | |
|---|---|---|
| UniProt AC | Q1WIM3 | |
| Protein Name | Cell adhesion molecule 3 | |
| Gene Name | Cadm3 | |
| Organism | Rattus norvegicus (Rat). | |
| Sequence Length | 396 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein . Cell junction . |
|
| Protein Description | Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity).. | |
| Protein Sequence | MGAPSALPLLLLLACSWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLAWRKGDQELHGDQTRIQEDPNGKTFTVSSSVSFQVTRDDDGANVVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPEPAHPREGQKLLLHCEGRGNPVPQQYVWVKEGSEPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYTAYFTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 130 | Acetylation | TVLGIPQKPIITGYK HHHCCCCCCEEECCH | 32.60 | 22902405 | |
| 288 | N-linked_Glycosylation | ALIFPFLNKSDSGTY EEEEECCCCCCCCCC | 42.01 | - | |
| 386 | Phosphorylation | INAEGGQSGGDDKKE EECCCCCCCCCCCCC | 48.28 | 30240740 | |
| 391 | Ubiquitination | GQSGGDDKKEYFI-- CCCCCCCCCCCCC-- | 52.85 | - | |
| 392 | Ubiquitination | QSGGDDKKEYFI--- CCCCCCCCCCCC--- | 65.72 | - | |
| 394 | Phosphorylation | GGDDKKEYFI----- CCCCCCCCCC----- | 18.56 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CADM3_RAT !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CADM3_RAT !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CADM3_RAT !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CADM3_RAT !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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