| UniProt ID | CADH7_HUMAN | |
|---|---|---|
| UniProt AC | Q9ULB5 | |
| Protein Name | Cadherin-7 | |
| Gene Name | CDH7 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 785 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. |
|
| Protein Description | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.. | |
| Protein Sequence | MKLGKVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQESLYS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 37 | Phosphorylation | SRSRSKPYFQSGRSR HHHCCCCCCCCCCCC | 20.28 | 30631047 | |
| 84 | Phosphorylation | KGDGSIKYILSGEGA CCCCCEEEEEECCCC | 12.86 | 25849741 | |
| 118 | Phosphorylation | DREEQAYYTLRAQAL CHHHHHHHHHHHHHH | 11.43 | 22817900 | |
| 119 | Phosphorylation | REEQAYYTLRAQALD HHHHHHHHHHHHHHH | 9.33 | 24719451 | |
| 193 | Phosphorylation | GNSARVVYSILQGQP CCCCHHHHHHHCCCC | 6.27 | - | |
| 226 | Phosphorylation | DREAKDQYLLVIQAK CHHHHHEEEEEEEEH | 16.49 | - | |
| 267 | Phosphorylation | PRFPRRSYQYNVPES CCCCCCCEECCCCCC | 17.13 | - | |
| 299 | Phosphorylation | GANAEMEYKIVDGDG CCCCEEEEEEECCCC | 12.52 | 21130716 | |
| 313 | Phosphorylation | GLGIFKISVDKETQE CEEEEEEEECCCCCE | 25.50 | 24719451 | |
| 338 | Phosphorylation | FEAKTSYTLRIEAAN CCEEEEEEEEEEECC | 14.88 | 24719451 | |
| 419 | Phosphorylation | RYSIDRNTDLERYFN EEEECCCCCHHHHEE | 42.74 | - | |
| 431 | Phosphorylation | YFNIDANSGVITTAK HEEECCCCCCEEECH | 35.84 | - | |
| 435 | Phosphorylation | DANSGVITTAKSLDR CCCCCCEEECHHHCC | 20.49 | - | |
| 436 | Phosphorylation | ANSGVITTAKSLDRE CCCCCEEECHHHCCC | 22.44 | - | |
| 439 | Phosphorylation | GVITTAKSLDRETNA CCEEECHHHCCCCCH | 32.79 | 24719451 | |
| 449 | N-linked_Glycosylation | RETNAIHNITVLAME CCCCHHHEEEEEEEC | 26.05 | UniProtKB CARBOHYD | |
| 461 | Phosphorylation | AMESQNPSQVGRGYV EECCCCHHHCCCCEE | 45.08 | - | |
| 530 | N-linked_Glycosylation | TDATNNHNFSLKDNK ECCCCCCCCCCCCCC | 30.26 | UniProtKB CARBOHYD | |
| 532 | Phosphorylation | ATNNHNFSLKDNKDN CCCCCCCCCCCCCCC | 39.57 | - | |
| 542 | Phosphorylation | DNKDNTASILTRRNG CCCCCHHHHHHCCCC | 18.98 | 24719451 | |
| 556 | Phosphorylation | GFRRQEQSVYYLPIF CCCCCCCEEEEEEEE | 16.01 | 24043423 | |
| 558 | Phosphorylation | RRQEQSVYYLPIFIV CCCCCEEEEEEEEEE | 12.44 | 24043423 | |
| 559 | Phosphorylation | RQEQSVYYLPIFIVD CCCCEEEEEEEEEEC | 12.12 | 24043423 | |
| 567 | Phosphorylation | LPIFIVDSGSPSLSS EEEEEECCCCCCCCC | 30.21 | 24043423 | |
| 569 | Phosphorylation | IFIVDSGSPSLSSTN EEEECCCCCCCCCCC | 18.44 | 24043423 | |
| 571 | Phosphorylation | IVDSGSPSLSSTNTL EECCCCCCCCCCCEE | 42.45 | 24043423 | |
| 573 | Phosphorylation | DSGSPSLSSTNTLTI CCCCCCCCCCCEEEE | 39.18 | 24043423 | |
| 574 | Phosphorylation | SGSPSLSSTNTLTIR CCCCCCCCCCEEEEE | 30.85 | 24043423 | |
| 575 | Phosphorylation | GSPSLSSTNTLTIRV CCCCCCCCCEEEEEE | 28.93 | 24043423 | |
| 577 | Phosphorylation | PSLSSTNTLTIRVCD CCCCCCCEEEEEEEC | 25.93 | 24043423 | |
| 579 | Phosphorylation | LSSTNTLTIRVCDCD CCCCCEEEEEEECCC | 12.52 | 24043423 | |
| 635 | Acetylation | VTMRRRKKEPLIFDE HHHHHCCCCCCCCCC | 63.85 | 11795033 | |
| 687 | Phosphorylation | TKTRRDVTPEIQFLS CCCCCCCCHHHHHHC | 21.35 | 26471730 | |
| 778 | Phosphorylation | RLADMYGTGQESLYS HHHHHHCCCCHHCCC | 20.43 | 28509920 | |
| 782 | Phosphorylation | MYGTGQESLYS---- HHCCCCHHCCC---- | 25.39 | 28509920 | |
| 785 | Phosphorylation | TGQESLYS------- CCCHHCCC------- | 38.75 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CADH7_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CADH7_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CADH7_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| FGF21_HUMAN | FGF21 | physical | 21988832 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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