CAD24_HUMAN - dbPTM
CAD24_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CAD24_HUMAN
UniProt AC Q86UP0
Protein Name Cadherin-24
Gene Name CDH24
Organism Homo sapiens (Human).
Sequence Length 819
Subcellular Localization Cell membrane
Single-pass type I membrane protein .
Protein Description Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion..
Protein Sequence MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
90PhosphorylationLTGEGAGTVFVIDEA
EECCCCCEEEEEEEC
15.38-
250PhosphorylationTTVTVTLSDVNDNPP
EEEEEEEHHCCCCCC
30.10-
258AcetylationDVNDNPPKFPQSLYQ
HCCCCCCCCCCCEEE
71.5720167786
262PhosphorylationNPPKFPQSLYQFSVV
CCCCCCCCEEEEEEE
29.3128111955
264PhosphorylationPKFPQSLYQFSVVET
CCCCCCEEEEEEEEE
16.8628111955
267PhosphorylationPQSLYQFSVVETAGP
CCCEEEEEEEEEECC
15.1028111955
271PhosphorylationYQFSVVETAGPGTLV
EEEEEEEEECCCCEE
25.8828111955
276PhosphorylationVETAGPGTLVGRLRA
EEEECCCCEEEEEEE
22.7728111955
360PhosphorylationGPFKDVASVRVAVQD
CCCCCCEEEEEEEEC
15.4224719451
446N-linked_GlycosylationREARAWHNLTVLATE
HHHHHHHHHEEEEHH
27.06UniProtKB CARBOHYD
473PhosphorylationPLLVAEWSAPAAPPQ
EEEEEEECCCCCCCC
18.84-
548N-linked_GlycosylationLDRDEVGNSSHVSFQ
CCCCCCCCCCCEEEC
45.58UniProtKB CARBOHYD
563N-linked_GlycosylationGPLGPDANFTVQDNR
CCCCCCCCCEEEECC
40.27UniProtKB CARBOHYD
573PhosphorylationVQDNRDGSASLLLPS
EEECCCCCEEEEEEC
20.97-
575PhosphorylationDNRDGSASLLLPSRP
ECCCCCEEEEEECCC
22.65-
580PhosphorylationSASLLLPSRPAPPRH
CEEEEEECCCCCCCC
51.3625278378

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CAD24_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CAD24_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CAD24_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CAD24_HUMAN !!

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CAD24_HUMAN

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Related Literatures of Post-Translational Modification

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