| UniProt ID | CAD11_MOUSE | |
|---|---|---|
| UniProt AC | P55288 | |
| Protein Name | Cadherin-11 | |
| Gene Name | Cdh11 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 796 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. |
|
| Protein Description | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.. | |
| Protein Sequence | MKENYCLQAALVCLSMLYHSQAFALERRSHLHPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVAIRVLDVNDNAPKFAAPYEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLPPEIMHNPNFTVRDNRDNTAGVYARRGGFSRQKQDFYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 455 | N-linked_Glycosylation | REETAWLNISVFAAE HHHHHEEEEEEHHHH | 17.49 | - | |
| 540 | N-linked_Glycosylation | PEIMHNPNFTVRDNR HHHHCCCCCEEECCC | 51.00 | - | |
| 568 | Phosphorylation | SRQKQDFYLLPIVIS CCCCCCEEEEEEEEE | 18.67 | - | |
| 700 | Phosphorylation | RKDIKPEYQYMPRPG HHHCCCHHCCCCCCC | 17.30 | 25338131 | |
| 702 | Phosphorylation | DIKPEYQYMPRPGLR HCCCHHCCCCCCCCC | 14.26 | 27717184 | |
| 714 | Phosphorylation | GLRPAPNSVDVDDFI CCCCCCCCCCHHHHH | 20.73 | 26824392 | |
| 723 | Phosphorylation | DVDDFINTRIQEADN CHHHHHHHHHHHCCC | 25.08 | 29550500 | |
| 757 | Phosphorylation | SVAGSLSSLESATTD CCCCCHHHHHCCCCC | 41.26 | 25195567 | |
| 786 | Phosphorylation | FKKLADLYGSKDTFD HHHHHHHHCCCCCCC | 21.65 | 25619855 | |
| 788 | Phosphorylation | KLADLYGSKDTFDDD HHHHHHCCCCCCCCC | 17.50 | 25521595 | |
| 791 | Phosphorylation | DLYGSKDTFDDDS-- HHHCCCCCCCCCC-- | 32.47 | 21082442 | |
| 796 | Phosphorylation | KDTFDDDS------- CCCCCCCC------- | 49.46 | 25619855 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CAD11_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CAD11_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CAD11_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CAD11_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-714, AND MASSSPECTROMETRY. | |
