dbPTM

CA131_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CA131_MOUSE
UniProt AC	Q8CIL4
Protein Name	Uncharacterized protein C1orf131 homolog
Gene Name
Organism	Mus musculus (Mouse).
Sequence Length	281
Subcellular Localization	Chromosome .
Protein Description
Protein Sequence	MAAEHDSDSVEPPGSEALLDAVLRTLYDLGETEGETEQKRIRKKKAKKRDSETIEDVAVEPLPLPGSPVRGQKKSASSFFQKLREELQSAPAAPSEVPVTTAVSLSPPKNGSKLVEVVEFQSKSKKRKLKSDEDEPAKNKTKVVKKDVDIQEFNLEKARLEVHRFGITGYGKGKERVLERERAIMLGAKPPKNTYVNYKVLQKQIKEKKIAVEEEKRAARETDIFKKKKKKGRGQEDRRSKKSAPSILSSGQVGQVGKFRNGTLILSPTDIKKINSSRVAK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MAAEHDSDSVEPPG -CCCCCCCCCCCCCC	33.42	26824392
9	Phosphorylation	AAEHDSDSVEPPGSE CCCCCCCCCCCCCHH	32.12	24068923
15	Phosphorylation	DSVEPPGSEALLDAV CCCCCCCHHHHHHHH	26.01	25159016
51	Phosphorylation	KKAKKRDSETIEDVA HHHHCCCCCCHHHCC	40.44	22942356
53	Phosphorylation	AKKRDSETIEDVAVE HHCCCCCCHHHCCCE	33.35	25619855
67	Phosphorylation	EPLPLPGSPVRGQKK EECCCCCCCCCCCCH	20.48	27087446
75	Phosphorylation	PVRGQKKSASSFFQK CCCCCCHHHHHHHHH	40.18	-
100	Phosphorylation	APSEVPVTTAVSLSP CCCCCCCEEEEECCC	11.72	25619855
101	Phosphorylation	PSEVPVTTAVSLSPP CCCCCCEEEEECCCC	25.87	25619855
104	Phosphorylation	VPVTTAVSLSPPKNG CCCEEEEECCCCCCC	22.21	25619855
106	Phosphorylation	VTTAVSLSPPKNGSK CEEEEECCCCCCCCC	31.48	26824392
112	Phosphorylation	LSPPKNGSKLVEVVE CCCCCCCCCEEEEEE	32.01	25619855
131	Phosphorylation	SKKRKLKSDEDEPAK HHCCCCCCCCCCCCC	57.58	26824392
172	Acetylation	FGITGYGKGKERVLE CCCCCCCCCHHHHHH	59.32	-
195	Phosphorylation	AKPPKNTYVNYKVLQ CCCCCCCCCCHHHHH	8.97	29514104
222	Phosphorylation	EKRAARETDIFKKKK HHHHHHHCHHHHHHH	28.92	25619855
267	Phosphorylation	RNGTLILSPTDIKKI CCCEEEECHHHHHHH	20.82	23984901
269	Phosphorylation	GTLILSPTDIKKINS CEEEECHHHHHHHCC	47.16	26745281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
53	T	Phosphorylation	Kinase	MTOR	Q9JLN9	PSP
67	S	Phosphorylation	Kinase	MTOR	Q9JLN9	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CA131_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CA131_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CA131_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CA131_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-67, AND MASSSPECTROMETRY.	17242355 [Abstract]