C295L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: C295L_HUMAN
• UniProt AC: Q96MC4
• Protein Name: CEP295 N-terminal-like protein {ECO:0000305}
• Gene Name: CEP295NL {ECO:0000312|HGNC:HGNC:44659}
• Organism: Homo sapiens (Human).
• Sequence Length: 621
• Subcellular Localization: Cell projection, cilium. Colocalizes to the motile cilium of mature spermatozoa..
• Protein Sequence: MCSGWSSSVIWRHTQFAVERCGFCGSSGPGAPLEPSTLGSKHLPWEAVSAGFADRNRNMDGAMWLSLCPDNEDLLWRKKHKLLQARGKGDLALQRRADAKLWKNYQLQRLAEELRRGYQEAQHLHVGGLDRLQSARLLGWGGGRARENEPDSQGPIQRRSARPPRAKEKHRAALSEERSCREELGQQHPRHSRPRKTAASPEKPQTTKATGRMNSHLAPPEKRKGRPEPSTKSGGGRCAIHPRRSKGADLERSNPLVAAVGEIGLVEEKEKGTARAGRRQLGKGAVCFVPALTSRSQGQSLEGKLRDLGQLWPADSSCRREAVSPASQCTLREKNKWQKELELAFEELFNINRKLKKHLCLYLALKPRMDQRPGEGHAFSEMQECGAGTPRGKKMADPEMLPAGEPRSPAEEEAQQAASKTDLKTFMGKAQNQKYQGTVKPTFRNGSQTLSPEAGIFINKEDSLLYSTESGQETPKLGTLAEGSLQLHLQDQADRVGSTASRQRQKAEMEQRRQKQLESLEQMEHPDMSLEIHYKAELEKERREQRRARLAHLKSSSTRAQERERGSELSTTSPSGTSLADDDRHSQMIRDQQQQILQQNRLHKQFLEEARKCLREFQNIC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
152	Phosphorylation	ARENEPDSQGPIQRR CCCCCCCCCCCCCCC		-
160	Phosphorylation	QGPIQRRSARPPRAK CCCCCCCCCCCCCHH		27282143
197	Phosphorylation	RHSRPRKTAASPEKP CCCCCCCCCCCCCCC		30622161
200	Phosphorylation	RPRKTAASPEKPQTT CCCCCCCCCCCCCCC		30622161
206	Phosphorylation	ASPEKPQTTKATGRM CCCCCCCCCCCCCCC		30622161
207	Phosphorylation	SPEKPQTTKATGRMN CCCCCCCCCCCCCCC		30622161
230	Phosphorylation	RKGRPEPSTKSGGGR CCCCCCCCCCCCCCC		28122231
231	Phosphorylation	KGRPEPSTKSGGGRC CCCCCCCCCCCCCCC		28122231
233	Phosphorylation	RPEPSTKSGGGRCAI CCCCCCCCCCCCCEE		28122231
253	Phosphorylation	KGADLERSNPLVAAV CCCCCCCCCHHHHHH		30622161
293	Phosphorylation	VCFVPALTSRSQGQS EEEECCCCCHHHCCC		30622161
294	Phosphorylation	CFVPALTSRSQGQSL EEECCCCCHHHCCCC		30622161
296	Phosphorylation	VPALTSRSQGQSLEG ECCCCCHHHCCCCCC		22985185
300	Phosphorylation	TSRSQGQSLEGKLRD CCHHHCCCCCCHHHH		30622161
408	Phosphorylation	LPAGEPRSPAEEEAQ CCCCCCCCHHHHHHH		30622161
419	Phosphorylation	EEAQQAASKTDLKTF HHHHHHHHHCCHHHH		30622161
467	Phosphorylation	KEDSLLYSTESGQET CCCCEEEECCCCCCC		27050516
586	Phosphorylation	LADDDRHSQMIRDQQ CCCCHHHHHHHHHHH		22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of C295L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of C295L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of C295L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of C295L_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.