dbPTM

C19L2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	C19L2_DROME
UniProt AC	Q9VXT5
Protein Name	CWF19-like protein 2 homolog
Gene Name	CG9213
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	687
Subcellular Localization
Protein Description
Protein Sequence	MSYIQFESGREKDKARQELREAREAMLQQAKERAELRGQRERQKELRGEADWMLPALAKKLEKPAKKSKKNVSKHKSRSKSKSSKKSRKHRNSSSSSESSTSSSSSFSEDEKERKRRKKKSKRSRKESASEDEWVEAPPPLAADNVTKKEPPQRDDWMTSESLLLKTFSRERKEPAKPNEKAQQIDAYDPAKSGRELNPYWKSNGTGLPGFQKPQDDDERQAKPHSSSSAQGSSRGWRKPGAKAPSPPRRSRSRSKSATSSDEEEEEAVQQPKSRPSCLTDEQINELAGKAIKAELKGKKELAAELNQQLEAARKERAEFIASGESVRNANTRPAKSKASAEHVLLTKVDQSGNVRPLVQSGDPNESYGGRMGPKRGSKKVDTHVDGQRVRYFADDDRYDIKQMFEREKHATAAEVNLQYADIVSKHKNPNDDLDDIFADKVRKQISASDAEKREMQSAIREHEKLVATLDNCERCFDSAKLDKQLLVSLGDKIYLSLPWYMGLQSGHCILTTLQHVPCCTQLDEDAWEEISNFRKALTRMFAARRQDVVFYEIANKLHRRPHLSVHCIPIPASQGEMAPFYFKKAIEESEQEWCINKQLVSLRQKSLRAAIPKGLPYVWVHFGMDSGFAHVIEDEDRFPANFAQEILGGMLELNPNAWRKPRKEANPIGKVKSFAENWKKFDCTQN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
124	Phosphorylation	RKKKSKRSRKESASE HHHHHHHHHHHCCCC	51.98	21082442
128	Phosphorylation	SKRSRKESASEDEWV HHHHHHHCCCCCCCC	39.88	19429919
130	Phosphorylation	RSRKESASEDEWVEA HHHHHCCCCCCCCCC	55.66	19429919
147	Phosphorylation	PLAADNVTKKEPPQR CCCCCCCCCCCCCCC	42.53	25749252

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of C19L2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of C19L2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of C19L2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of C19L2_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of C19L2_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-128 AND SER-130, ANDMASS SPECTROMETRY.	18327897 [Abstract]