| UniProt ID | BZW1_MOUSE | |
|---|---|---|
| UniProt AC | Q9CQC6 | |
| Protein Name | Basic leucine zipper and W2 domain-containing protein 1 | |
| Gene Name | Bzw1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 419 | |
| Subcellular Localization | ||
| Protein Description | Enhances histone H4 gene transcription but does not seem to bind DNA directly.. | |
| Protein Sequence | MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MNNQKQQK -------CCCCCCCC | 10.83 | 16452087 | |
| 10 | Phosphorylation | NQKQQKPTLSGQRFK CCCCCCCCCCCHHHC | 40.36 | 28066266 | |
| 12 | Phosphorylation | KQQKPTLSGQRFKTR CCCCCCCCCHHHCCC | 35.04 | 28066266 | |
| 35 | Glutathionylation | DPTQFQDCIIQGLTE CHHHHHHHHHHHHCC | 1.73 | 24333276 | |
| 66 | Phosphorylation | AKLDYRRYAETLFDI CCCCHHHHHHHHHHH | 10.37 | 25777480 | |
| 69 | Phosphorylation | DYRRYAETLFDILVA CHHHHHHHHHHHHHH | 25.26 | 25777480 | |
| 85 | Phosphorylation | GMLAPGGTLADDMMR CCCCCCCCCHHHHHH | 25.37 | 25777480 | |
| 96 | Glutathionylation | DMMRTDVCVFAAQED HHHHCCHHHEECHHH | 2.01 | 24333276 | |
| 205 | Phosphorylation | DINAVAASLRKVSMD HHHHHHHHHHHHCCC | 20.97 | 29176673 | |
| 210 | Phosphorylation | AASLRKVSMDNRLME HHHHHHHCCCCHHHH | 24.37 | 30387612 | |
| 223 | Ubiquitination | MELFPANKQSVEHFT HHHCCCCHHHHHHHH | 46.16 | 22790023 | |
| 259 | Ubiquitination | GARKELQKELQEQMS HHHHHHHHHHHHHHH | 73.37 | 22790023 | |
| 272 | Ubiquitination | MSRGDPFKDIILYVK HHCCCCHHHHHHHHH | 54.10 | 22790023 | |
| 391 | Phosphorylation | AHVAKGKSVFLEQMK HHHHCCCHHHHHHHH | 27.11 | 29514104 | |
| 398 | Acetylation | SVFLEQMKKFVEWLK HHHHHHHHHHHHHHH | 42.63 | 15609857 | |
| 411 | Phosphorylation | LKNAEEESESEAEEG HHCHHHHHHHHHHCC | 50.10 | 25521595 | |
| 413 | Phosphorylation | NAEEESESEAEEGD- CHHHHHHHHHHCCC- | 51.92 | 25521595 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BZW1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BZW1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BZW1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of BZW1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-411 AND SER-413, ANDMASS SPECTROMETRY. | |
