BTG3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BTG3_HUMAN
• UniProt AC: Q14201
• Protein Name: Protein BTG3
• Gene Name: BTG3
• Organism: Homo sapiens (Human).
• Sequence Length: 252
• Protein Description: Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase..
• Protein Sequence: MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENKDENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDRNHWINPHMLAPH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	AAVVFFFTRLVRKHD HHHHHHHHHHHHHHH	20.24	-
43	Ubiquitination	LILQEKYKNHWYPEK HHHHHHHCCCCCCCC	54.10	-
50	Ubiquitination	KNHWYPEKPSKGQAY CCCCCCCCCCCCCCE	50.52	-
53	Ubiquitination	WYPEKPSKGQAYRCI CCCCCCCCCCCEEEE	64.67	-
74	Ubiquitination	RVDPDVLKACENSCI CCCHHHHHHHCCCEE	51.33	-
108	Ubiquitination	VCCRYGEKNNAFIVA HHHHHCCCCCEEEEE	51.65	2190698
108 (in isoform 1)	Ubiquitination	-	51.65	21906983
120	Ubiquitination	IVASFENKDENKDEI EEEEEECCCCCHHHH	60.26	-
137	Ubiquitination	KVTRALDKVTSDYHS HHHHHHHHHHHCCCC	48.54	-
139	Phosphorylation	TRALDKVTSDYHSGS HHHHHHHHHCCCCCC	22.94	23090842
140	Phosphorylation	RALDKVTSDYHSGSS HHHHHHHHCCCCCCC	38.88	23090842
142	Phosphorylation	LDKVTSDYHSGSSSS HHHHHHCCCCCCCCC	9.54	23090842
144	Phosphorylation	KVTSDYHSGSSSSDE HHHHCCCCCCCCCCH	33.85	23663014
146	Phosphorylation	TSDYHSGSSSSDEET HHCCCCCCCCCCHHH	30.02	23663014
147	Phosphorylation	SDYHSGSSSSDEETS HCCCCCCCCCCHHHH	37.07	23663014
148	Phosphorylation	DYHSGSSSSDEETSK CCCCCCCCCCHHHHH	43.43	23663014
149	Phosphorylation	YHSGSSSSDEETSKE CCCCCCCCCHHHHHC	51.49	25159151
153	Phosphorylation	SSSSDEETSKEMEVK CCCCCHHHHHCEEEC	42.95	23090842
154	Phosphorylation	SSSDEETSKEMEVKP CCCCHHHHHCEEECH	29.87	23090842
169	Phosphorylation	SSVTAAASPVYQISE HHHHCCCCCCEEHHH	15.35	25159151
172	Phosphorylation	TAAASPVYQISELIF HCCCCCCEEHHHHHC	11.96	-
191	Phosphorylation	MWHPLPRKKPGMYRG CCCCCCCCCCCCCCC	62.47	27251275
192	Phosphorylation	WHPLPRKKPGMYRGN CCCCCCCCCCCCCCC	48.35	27251275
196	Phosphorylation	PRKKPGMYRGNGHQN CCCCCCCCCCCCCCC	22.68	18083107
205	Phosphorylation	GNGHQNHYPPPVPFG CCCCCCCCCCCCCCC	25.61	-
213	Phosphorylation	PPPVPFGYPNQGRKN CCCCCCCCCCCCCCC	10.21	18083107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BTG3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BTG3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BTG3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CHK1_HUMAN	CHEK1	physical	23533280

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.