BTBDG_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BTBDG_HUMAN
• UniProt AC: Q32M84
• Protein Name: BTB/POZ domain-containing protein 16
• Gene Name: BTBD16
• Organism: Homo sapiens (Human).
• Sequence Length: 506
• Protein Sequence: MIMSNTHKARLERRVTGSTNRWRLPKQPFSGDLLSLSQMCKALSIDFEEALRNPDRLCISQIQKFFFENFKNKDIQSGEADVILECLGFKWELHQPQLFQSETLAKLYLKALAQGTTHPLRELEELLRAQSPKKTKEKSPAKRIIISLKINDPLVTKVAFATALKNLYMSEVEINLEDLLGVLASAHILQFSGLFQRCVDVMIARLKPSTIKKFYEAGCKYKEEQLTTGCEKWLEMNLVPLGGTQIHLHKIPQDLLHKVLKSPRLFTFSEFHLLKTMLLWVFLQLNYKIQAIPTYETVMTFFKSFPENCCFLDRDIGRSLRPLFLCLRLHGITKGKDLEVLRHLNFFPESWLDQVTVNHYHALENGGDMVHLKDLNTQAVRFGLLFNQENTTYSKTIALYGFFFKIKGLKHDTTSYSFYMQRIKHTDLESPSAVYEHNHVSLRAARLVKYEIRAEALVDGKWQEFRTNQIKQKFGLTTSSCKSHTLKIQTVGIPIYVSFAFIFPAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	O-linked_Glycosylation	----MIMSNTHKARL ----CCCCCCCHHHH	27.87	30379171
30	Phosphorylation	RLPKQPFSGDLLSLS CCCCCCCCCCHHHHH	37.77	19845377
35	Phosphorylation	PFSGDLLSLSQMCKA CCCCCHHHHHHHHHH	33.02	30622161
37	Phosphorylation	SGDLLSLSQMCKALS CCCHHHHHHHHHHHC	16.70	19845377
44	Phosphorylation	SQMCKALSIDFEEAL HHHHHHHCCCHHHHH	25.60	28842319
131	Phosphorylation	EELLRAQSPKKTKEK HHHHHCCCCCCCCCC	37.39	24825855
147	Phosphorylation	PAKRIIISLKINDPL CCCEEEEEEEECCHH	17.13	24719451
156	Phosphorylation	KINDPLVTKVAFATA EECCHHHHHHHHHHH	27.73	-
207	Acetylation	DVMIARLKPSTIKKF HHHHHHCCHHHHHHH	31.22	7355449
220	Acetylation	KFYEAGCKYKEEQLT HHHHCCCCCCHHHHC	59.44	25038526
267	Phosphorylation	LKSPRLFTFSEFHLL HHCCCCCCHHHHHHH	30.73	24719451
288	Methylation	VFLQLNYKIQAIPTY HHHHHCCCCCCCCCH	27.54	23644510
288	"N6,N6-dimethyllysine"	VFLQLNYKIQAIPTY HHHHHCCCCCCCCCH	27.54	-
297	Phosphorylation	QAIPTYETVMTFFKS CCCCCHHHHHHHHHH	12.74	29759185
300	Phosphorylation	PTYETVMTFFKSFPE CCHHHHHHHHHHCCC	22.91	29759185
477	Phosphorylation	IKQKFGLTTSSCKSH HHHHHCCCHHHCCCC	25.63	24719451
478	Phosphorylation	KQKFGLTTSSCKSHT HHHHCCCHHHCCCCE	24.56	-
479	Phosphorylation	QKFGLTTSSCKSHTL HHHCCCHHHCCCCEE	28.62	-
480	Phosphorylation	KFGLTTSSCKSHTLK HHCCCHHHCCCCEEE	24.38	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BTBDG_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BTBDG_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BTBDG_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of BTBDG_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.