BTBDB_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BTBDB_MOUSE
• UniProt AC: Q6GQW0
• Protein Name: Ankyrin repeat and BTB/POZ domain-containing protein BTBD11
• Gene Name: Btbd11
• Organism: Mus musculus (Mouse).
• Sequence Length: 1109
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELELLLLRSRDPRAGPAVPGSLPKDALAKLSMLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVLASGLPRSCSGPGPGSSSGSGPGPGSGPGAPAADKERETPGGGAASGGPCSAASSASGGSSCCAPPATAATAVPPTTATAAVAANHHHHHHTLHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLSLPESLNLHRDPQRPSKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPMHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLKADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDNTCIEIGYVKYPIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYSHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGAGQDVLQDLQRTLAIRIQSIHLSSSKGSVV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
65	Phosphorylation	SMHSRHNSFDTVNTA HHHHCCCCCCCCCHH	20.55	24719451
151	Phosphorylation	AKEAQRLSLRFAKCT HHHHHHHHHHHHHCC	21.49	24704852
260	Phosphorylation	LASGLPRSCSGPGPG HHHCCCCCCCCCCCC	15.64	29899451
262	Phosphorylation	SGLPRSCSGPGPGSS HCCCCCCCCCCCCCC	49.63	29899451
268	Phosphorylation	CSGPGPGSSSGSGPG CCCCCCCCCCCCCCC	25.19	29899451
456	Phosphorylation	AKHHGNGTPMHHKQG CCCCCCCCCCCCCCC	22.80	29899451
526	Phosphorylation	AHAGHRRSFSMDSDD HHCCCCCCCCCCHHH	22.94	-
768	Phosphorylation	KEKSDILSLEEILAE HHHHCCCCHHHHHHH	33.78	29899451
940	Phosphorylation	LVEGRPFYAHKVLLF EECCCEEEEEEEEEE	15.52	25777480
948	Phosphorylation	AHKVLLFTASPRFKA EEEEEEEECCHHHHH	26.62	25777480
950	Phosphorylation	KVLLFTASPRFKALL EEEEEECCHHHHHHH	17.35	25777480

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BTBDB_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BTBDB_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BTBDB_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of BTBDB_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.