BTBDB_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BTBDB_HUMAN
• UniProt AC: A6QL63
• Protein Name: Ankyrin repeat and BTB/POZ domain-containing protein BTBD11
• Gene Name: BTBD11
• Organism: Homo sapiens (Human).
• Sequence Length: 1104
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTAAALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGSGPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSEIWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQMEWENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGVDCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTMSEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLHGHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMYRNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPPPLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRPLIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPKLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDGTCIEIGYVKYSIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAKSINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVLQDLQRTLAIRIQSIHLSSSKGSVV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Methylation	-----MARRGKKPVV -----CCCCCCCCCE	60.80	-
39	Phosphorylation	SNLSLCCSDSHPASP CCCEEECCCCCCCCC	40.94	30576142
47	Phosphorylation	DSHPASPYGGSCWPP CCCCCCCCCCCCCCC	31.46	30576142
65	Phosphorylation	SMHSRHNSFDTVNTA HHHHCCCCCCCCCHH	20.55	22617229
68	Phosphorylation	SRHNSFDTVNTALVE HCCCCCCCCCHHHHC	17.41	29116813
71	Phosphorylation	NSFDTVNTALVEDSE CCCCCCCHHHHCCCC	19.62	27732954
111	Phosphorylation	LEALLLRSRDPRAGP HHHHHHHCCCCCCCC	40.79	-
151	Phosphorylation	AKEAQRLSLRFAKCT HHHHHHHHHHHHHCC	21.49	23532336
210	Phosphorylation	KSARCGLTFSVGRVY CCCCCCCEEECCHHH	10.11	-
250	Phosphorylation	SLFRDIYSRVVASGV HHHHHHHHHHHHCCC	20.95	24719451
260	Phosphorylation	VASGVPRSCSGPGSG HHCCCCCCCCCCCCC	13.43	22210691
266	Phosphorylation	RSCSGPGSGSGSGPG CCCCCCCCCCCCCCC	32.68	22210691
268	Phosphorylation	CSGPGSGSGSGPGPS CCCCCCCCCCCCCCC	31.33	22210691
398	Ubiquitination	RDPQRSNKPGELPMF CCCCCCCCCCCCCCC	56.50	-
429	Phosphorylation	VGSIAELSDLVSRAM HHHHHHHHHHHHHHH	22.02	22210691
523	Phosphorylation	AGHRRSFSMDSDDVR CCCCCCCCCCHHHHH	23.95	-
558	Ubiquitination	DCFCASRKLDAVAIE CCEECCCCCCEEEEE	48.50	-
567	Ubiquitination	DAVAIEAKFKQDLGF CEEEEEHHHHCHHCC	40.06	-
569	Ubiquitination	VAIEAKFKQDLGFRM EEEEHHHHCHHCCCC	42.04	-
721	Dimethylation	PLIGTMYRNGISTTP CCCCCCCCCCCCCCC	24.87	-
721	Methylation	PLIGTMYRNGISTTP CCCCCCCCCCCCCCC	24.87	-
749	Ubiquitination	GHRNVFRKLLAQPEK CHHHHHHHHHCCCHH	36.07	-
851	Phosphorylation	CLLKEFKTIQEEEYT HHHHHHCCCCHHHHH	32.96	-
890	Phosphorylation	QQLCVIFTHCYGPYP HHHHHHHHHHCCCCC	10.42	22817900
893	Phosphorylation	CVIFTHCYGPYPIPK HHHHHHHCCCCCCCC	17.33	22817900
970	Phosphorylation	IEIGYVKYSIFQLVM EEEECCHHHHHHHHH	9.28	-
981	Phosphorylation	QLVMQYLYYGGPESL HHHHHHHHHCCHHHE	8.64	-
982	Phosphorylation	LVMQYLYYGGPESLL HHHHHHHHCCHHHEE	17.01	-
987	Phosphorylation	LYYGGPESLLIKNNE HHHCCHHHEEEECHH	31.44	19413330
1000	Phosphorylation	NEIMELLSAAKFFQL HHHHHHHHHHHHHHH	38.51	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BTBDB_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BTBDB_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BTBDB_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of BTBDB_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.