dbPTM

BTB6A_DANRE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BTB6A_DANRE
UniProt AC	A9JRD8
Protein Name	BTB/POZ domain-containing protein 6-A
Gene Name	btbd6a
Organism	Danio rerio (Zebrafish) (Brachydanio rerio).
Sequence Length	540
Subcellular Localization	Cytoplasm . Nucleus . Present mainly, but not excusively in the cytoplasm.
Protein Description	Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis..
Protein Sequence	MPAAPECRLSNHGRIMKCVTFLLLLPETLKKLKRASKHPGRLSVCYNILTLSLKKRMAAELYPVSDHATLQKSGAVMLSLPEKKRNVEPVSQTTASIATTPTTEQNINNNNVEIPSWHSAHPTLRERNALMFNNEQMADVHFIVGPPGESQRVPAHKYVLAVGSSVFCAMFYGDLAEGDSDIHIPDVEPAAFLILLKYMYSDEIELAPDTVLATLYAAKKYLVSALARACVGFLETSLEARNACVLLSQSRLFEEPELTQRCWEVIDAQAELALRSEGFSEIDLPTLESILHRETLNVKESVVFQAVLGWADAECRRQGLSPTSQNQRSVLGKALHLVRLPSMTLQEFADGAAQVDILTLEETHSIFLWYTAATKPSLGFPVNAREGLTAQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDKRVFIAGLGLYGSSGGKAEYSVRIELKRQGVLLAQNLTKFVSDGSSSTFPVWFEHPVQVEQDAFYTVSAVLDGSELSYFGQEGMTEVQCGKVTFQFQCSSDSTNGTGVQGGQIPELIFYA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of BTB6A_DANRE !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BTB6A_DANRE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BTB6A_DANRE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BTB6A_DANRE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BTB6A_DANRE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BTB6A_DANRE

Related Literatures of Post-Translational Modification