dbPTM

BRI3B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BRI3B_MOUSE
UniProt AC	Q8BXV2
Protein Name	BRI3-binding protein
Gene Name	Bri3bp {ECO:0000312\|MGI:MGI:1924059}
Organism	Mus musculus (Mouse).
Sequence Length	253
Subcellular Localization	Mitochondrion outer membrane Multi-pass membrane protein.
Protein Description	Involved in tumorigenesis and may function by stabilizing p53/TP53..
Protein Sequence	MGARASQEPRTRVRAGLRVLLPVLLLALLLLALVAPGAQGARGRGAADKNSHRRATSSFSQSVSSLFGEDNVRAAQKLLSRLTERFVQGVDMFLETLWKVWMELLEVLGLDVSNLSQYFSPASVSNSPTRALVLVGVVLLAYWFLSLTLGFTFSLLHLVFGRFFWLVRVILFSMSCVYILHKYEGEPEHAVLPLCVVVAIYFMTGPMGYWRGSPGGLCSPSVEEKLEHLENQVRLLNIRLNRVLENLDRSKDK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MGARASQEPRTRV --CCCCCCCCHHHHH	29.53	-
56	Phosphorylation	KNSHRRATSSFSQSV CCCCHHHHHHHHHHH	24.08	28066266
57	Phosphorylation	NSHRRATSSFSQSVS CCCHHHHHHHHHHHH	28.53	28066266
58	Phosphorylation	SHRRATSSFSQSVSS CCHHHHHHHHHHHHH	25.27	28066266
60	Phosphorylation	RRATSSFSQSVSSLF HHHHHHHHHHHHHHH	24.40	28066266
218	S-nitrosocysteine	RGSPGGLCSPSVEEK CCCCCCCCCCCHHHH	6.77	-
218	Glutathionylation	RGSPGGLCSPSVEEK CCCCCCCCCCCHHHH	6.77	24333276
218	S-nitrosylation	RGSPGGLCSPSVEEK CCCCCCCCCCCHHHH	6.77	21278135
221	Phosphorylation	PGGLCSPSVEEKLEH CCCCCCCCHHHHHHH	26.35	25521595
250	Phosphorylation	VLENLDRSKDK---- HHHHHHHCCCC----	44.89	21743459

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BRI3B_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BRI3B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BRI3B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BRI3B_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BRI3B_MOUSE

Related Literatures of Post-Translational Modification