BPIB3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BPIB3_HUMAN
• UniProt AC: P59826
• Protein Name: BPI fold-containing family B member 3
• Gene Name: BPIFB3
• Organism: Homo sapiens (Human).
• Sequence Length: 476
• Subcellular Localization: Secreted. Cytoplasm . According to PubMed:12837268, it is cytoplasmic.
• Protein Description: May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity)..
• Protein Sequence: MQPVMLALWSLLLLWGLATPCQELLETVGTLARIDKDELGKAIQNSLVGEPILQNVLGSVTAVNRGLLGSGGLLGGGGLLGHGGVFGVVEELSGLKIEELTLPKVLLKLLPGFGVQLSLHTKVGMHCSGPLGGLLQLAAEVNVTSRVALAVSSRGTPILILKRCSTLLGHISLFSGLLPTPLFGVVEQMLFKVLPGLLCPVVDSVLGVVNELLGAVLGLVSLGALGSVEFSLATLPLISNQYIELDINPIVKSVAGDIIDFPKSRAPAKVPPKKDHTSQVMVPLYLFNTTFGLLQTNGALDMDITPELVPSDVPLTTTDLAALLPEALGKLPLHQQLLLFLRVREAPTVTLHNKKALVSLPANIHVLFYVPKGTPESLFELNSVMTVRAQLAPSATKLHISLSLERLSVKVASSFTHAFDGSRLEEWLSHVVGAVYAPKLNVALDVGIPLPKVLNINFSNSVLEIVENAVVLTVAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
142	N-linked_Glycosylation	LQLAAEVNVTSRVAL HHHHHCCCCCCCEEH	23.89	UniProtKB CARBOHYD
152	Phosphorylation	SRVALAVSSRGTPIL CCEEHHHCCCCCEEE	14.54	28355574
153	Phosphorylation	RVALAVSSRGTPILI CEEHHHCCCCCEEEE	28.29	-
156	Phosphorylation	LAVSSRGTPILILKR HHHCCCCCEEEEHHH	13.17	-
180	Phosphorylation	LFSGLLPTPLFGVVE HHHCCCCCHHHHHHH	32.37	26853621
288	N-linked_Glycosylation	MVPLYLFNTTFGLLQ EEEHHHCCCCHHHHH	35.30	UniProtKB CARBOHYD
457	N-linked_Glycosylation	LPKVLNINFSNSVLE CCCEEEEECCCCHHH	32.97	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BPIB3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BPIB3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BPIB3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of BPIB3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.