BNC2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BNC2_MOUSE
• UniProt AC: Q8BMQ3
• Protein Name: Zinc finger protein basonuclin-2
• Gene Name: Bnc2 {ECO:0000312|MGI:MGI:2443805}
• Organism: Mus musculus (Mouse).
• Sequence Length: 1127
• Subcellular Localization: Nucleus .
• Protein Description: Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes..
• Protein Sequence: MARFVPSPPPNCLSYKSEGRLGEQDWQAHFKVPCCGVDPSQLESEEAEVDVRERDTQRDREPKRARDLTLRDSCTDNSMQFGTRTTAAEPGFMGTWQNADTNLLFRMSQQVPLACAGRVLGADFCPNLEEPDQRLEVQAIRCTLVNCTCECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQAVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSISTQNEYNESSESEVSPTPYKSDQTPNRNALTSITNVEPKTEPACVSPIQNSAPVSDLSKTEHPKSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLTLTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPPPPSEPIVPAVMMGTHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDPNDGGTVVNDMSHDNHCHSQDEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHLHSEVSEKVLMNSERPDENHSEPSHQDVIKVKEEFTDPTYDMFYMSQYGLYNGGGASMAALHESFTSSLNYGSPQKFSPEGDLCSSPDPKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMSLDSSQPSLSKDLRDEFLMKIYGAQHPLGLDGREDASSPAGTEDSHLNGYGRGMAEDYMVLDLSTTSSLQSSSSVHSSRESDAGSDEGILLDDIDGASDSGESTHKAEAPTLPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNIPFTSID

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MARFVPSPPPNCLS -CCCCCCCCCCCCCC	44.74	26824392
69	Phosphorylation	PKRARDLTLRDSCTD CHHHHCCCCHHHCCC	24.84	-
336	Phosphorylation	LENSNPSSIHHFENI HHCCCHHHHHCCCCC	27.48	24719451
384	Phosphorylation	GLRLREPSISTQNEY CCCCCCCCCCCCCCC	25.15	25338131
386	Phosphorylation	RLREPSISTQNEYNE CCCCCCCCCCCCCCC	28.42	25338131
387	Phosphorylation	LREPSISTQNEYNES CCCCCCCCCCCCCCC	33.47	25338131
391	Phosphorylation	SISTQNEYNESSESE CCCCCCCCCCCCCCC	31.60	26643407
394	Phosphorylation	TQNEYNESSESEVSP CCCCCCCCCCCCCCC	35.45	26643407
395	Phosphorylation	QNEYNESSESEVSPT CCCCCCCCCCCCCCC	38.67	26643407
397	Phosphorylation	EYNESSESEVSPTPY CCCCCCCCCCCCCCC	45.29	26643407
400	Phosphorylation	ESSESEVSPTPYKSD CCCCCCCCCCCCCCC	21.00	26643407
406	Phosphorylation	VSPTPYKSDQTPNRN CCCCCCCCCCCCCCC	26.81	26643407
409	Phosphorylation	TPYKSDQTPNRNALT CCCCCCCCCCCCCCC	27.54	26643407
416	Phosphorylation	TPNRNALTSITNVEP CCCCCCCCCCCCCCC	18.70	26643407
425	Phosphorylation	ITNVEPKTEPACVSP CCCCCCCCCCCCCCC	58.90	25619855
431	Phosphorylation	KTEPACVSPIQNSAP CCCCCCCCCCCCCCC	19.03	26824392
436	Phosphorylation	CVSPIQNSAPVSDLS CCCCCCCCCCHHHCC	19.99	25619855
440	Phosphorylation	IQNSAPVSDLSKTEH CCCCCCHHHCCCCCC	31.60	25619855
443	Phosphorylation	SAPVSDLSKTEHPKS CCCHHHCCCCCCCCC	42.39	25619855
542	Phosphorylation	DKDLIRATSGAATPV CHHHHHHCCCCCCCE	20.18	29550500
543	O-linked_Glycosylation	KDLIRATSGAATPVI HHHHHHCCCCCCCEE	26.00	51587817
543	Phosphorylation	KDLIRATSGAATPVI HHHHHHCCCCCCCEE	26.00	29550500
547	Phosphorylation	RATSGAATPVIASTK HHCCCCCCCEEEECC	19.97	26824392
555	Phosphorylation	PVIASTKSNLTLTSP CEEEECCCCEEECCC	36.84	26643407
558	Phosphorylation	ASTKSNLTLTSPGRP EECCCCEEECCCCCC	32.04	26643407
560	Phosphorylation	TKSNLTLTSPGRPPM CCCCEEECCCCCCCC	27.86	26643407
561	Phosphorylation	KSNLTLTSPGRPPMG CCCEEECCCCCCCCC	28.59	26643407
570	Phosphorylation	GRPPMGFTTPPLDPV CCCCCCCCCCCCCHH	32.44	26643407
571	Phosphorylation	RPPMGFTTPPLDPVL CCCCCCCCCCCCHHH	22.20	26643407
589	Phosphorylation	LPSQLVFSGLKTVQP CCHHHHCCCCCCCCC	35.42	-
612	Phosphorylation	LTPGEMVSPPTSLPT CCCCCCCCCCCCCCC	24.69	25338131
616	Phosphorylation	EMVSPPTSLPTSPII CCCCCCCCCCCCCCC	37.82	25338131
619	Phosphorylation	SPPTSLPTSPIIPTS CCCCCCCCCCCCCCC	53.05	25338131
620	Phosphorylation	PPTSLPTSPIIPTSG CCCCCCCCCCCCCCC	16.50	25338131
663	Acetylation	APKKKPRKSSMPVKI CCCCCCCCCCCCCEE	56.24	23576753
664	Phosphorylation	PKKKPRKSSMPVKIE CCCCCCCCCCCCEEE	32.90	25338131
665	Phosphorylation	KKKPRKSSMPVKIEK CCCCCCCCCCCEEEE	30.09	29514104
669	Acetylation	RKSSMPVKIEKEIID CCCCCCCEEEEEEEC	39.00	23576753
677	Phosphorylation	IEKEIIDTADEFDDE EEEEEECCCHHCCCC	26.12	25338131
706	Phosphorylation	SHDNHCHSQDEMSPG CCCCCCCCCCCCCCC	44.73	25338131
711	Phosphorylation	CHSQDEMSPGMSVKD CCCCCCCCCCCCHHH	19.09	25338131
738	Phosphorylation	TEIRRADSMTSEDQE HHHHHHHCCCCCCCC	23.99	25338131
741	Phosphorylation	RRADSMTSEDQEPER HHHHCCCCCCCCCCC	30.45	25338131
754	Phosphorylation	ERDYENESESSEPKL CCCCCCCCCCCCCCC	55.12	-
757	Phosphorylation	YENESESSEPKLGEE CCCCCCCCCCCCCCC	54.59	25521595
765	Phosphorylation	EPKLGEESMEGDEHL CCCCCCCCCCCCHHH	20.17	25521595
774	Phosphorylation	EGDEHLHSEVSEKVL CCCHHHHHHHHHHHH	46.16	25521595
792	Phosphorylation	ERPDENHSEPSHQDV CCCCCCCCCCCHHHH	63.89	29514104
849	Phosphorylation	YGSPQKFSPEGDLCS CCCCCCCCCCCCCCC	29.13	25619855
856	Phosphorylation	SPEGDLCSSPDPKIC CCCCCCCCCCCCCEE	52.80	25619855
857	Phosphorylation	PEGDLCSSPDPKICY CCCCCCCCCCCCEEE	32.12	25619855
868	Acetylation	KICYVCKKSFKSSYS CEEEEECHHHCCCEE	56.87	15606019
871	Acetylation	YVCKKSFKSSYSVKL EEECHHHCCCEEEEE	45.65	15606027
877	Acetylation	FKSSYSVKLHYRNVH HCCCEEEEEEEECCC	24.49	15606035
928	Phosphorylation	TKELDDMSLDSSQPS HHHHHHCCCCCCCCC	35.70	29514104
932	Phosphorylation	DDMSLDSSQPSLSKD HHCCCCCCCCCCCHH	45.86	22006019
949	Phosphorylation	DEFLMKIYGAQHPLG HHHHHHHHCCCCCCC	10.82	26643407
964	Phosphorylation	LDGREDASSPAGTED CCCCCCCCCCCCCCC	49.53	26643407
965	Phosphorylation	DGREDASSPAGTEDS CCCCCCCCCCCCCCC	22.08	26643407
969	Phosphorylation	DASSPAGTEDSHLNG CCCCCCCCCCCCCCC	38.43	26643407
972	Phosphorylation	SPAGTEDSHLNGYGR CCCCCCCCCCCCCCC	24.52	26643407
1012	Phosphorylation	SRESDAGSDEGILLD CCCCCCCCCCCEEEE	33.92	25338131
1025	Phosphorylation	LDDIDGASDSGESTH EECCCCCCCCCCCCC	37.53	25338131
1031	Phosphorylation	ASDSGESTHKAEAPT CCCCCCCCCCCCCCC	24.08	25338131
1084	Phosphorylation	TLRVHYKTVHLREMH EEEEEEEEEEHHHHH	13.14	22871156
1125	Phosphorylation	HKNIPFTSID----- CCCCCCCCCC-----	25.74	25338131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BNC2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BNC2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BNC2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of BNC2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.