BNB_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BNB_DROME
• UniProt AC: P29746
• Protein Name: Protein bangles and beads
• Gene Name: bnb
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 442
• Protein Description: May play an important role during development..
• Protein Sequence: MKCQLLFVATVCLASVWALPVPDEEVAIQPDSGAKAELLTKTVLPTAVEPAPLKPEAEKPAETKTIEAKAAVPEQPDVNANPSPSTPAAEPAKEINSVELKSSAPDVETAPAIPEKKTLPEEAKPAQENAPVEAEKKQEKTARTEAEPTVEAQPQATKAIEQAPEAPAANAEVQKQVVDEVKPQEPKIDAKSAEEPAIPAVVAAEKETPVPEQPARQERINEIEQKDAKKDAAVAEEPAKAAEATPTAAPEAATKSDSNIQVIAPEKKSIESSPAAAAASPAAQAAQAKSGEAPKPVDQQKSTETVAESAPVLKTNAPLAPAGATKVTEAVKEQEKEQPAADTAAKALPEQKKTEETAAPAGAPEPTAAVAPAAVPEAKKIDEAPAAETVVKGEEAIAKPIAQSPSAEPKKSSEEKSDKSESKVDESSESKESEESSESKEN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
97	Phosphorylation	EPAKEINSVELKSSA CCCHHCCCEEEHHCC	23.72	27794539
102	Phosphorylation	INSVELKSSAPDVET CCCEEEHHCCCCCCC	44.34	27794539
103	Phosphorylation	NSVELKSSAPDVETA CCEEEHHCCCCCCCC	42.08	27794539
192	Phosphorylation	EPKIDAKSAEEPAIP CCCCCCCCCCCCCCC	42.50	28490779
269	Phosphorylation	VIAPEKKSIESSPAA EECCCCCCCCCCHHH	42.53	27794539
290	Phosphorylation	AQAAQAKSGEAPKPV HHHHHHHCCCCCCCC	44.90	27794539
302	Phosphorylation	KPVDQQKSTETVAES CCCCCCCCCCCHHHH	27.43	27794539
303	Phosphorylation	PVDQQKSTETVAESA CCCCCCCCCCHHHHC	42.59	27794539
404	Phosphorylation	IAKPIAQSPSAEPKK CHHHHCCCCCCCCCC	16.29	27794539
406	Phosphorylation	KPIAQSPSAEPKKSS HHHCCCCCCCCCCCC	50.97	27794539
412	Phosphorylation	PSAEPKKSSEEKSDK CCCCCCCCCHHCCCH	49.46	27794539
413	Phosphorylation	SAEPKKSSEEKSDKS CCCCCCCCHHCCCHH	59.67	27794539
420	Phosphorylation	SEEKSDKSESKVDES CHHCCCHHHHHCCCC	52.68	27794539
427	Phosphorylation	SESKVDESSESKESE HHHHCCCCHHHHHHH	34.64	22817900
428	Phosphorylation	ESKVDESSESKESEE HHHCCCCHHHHHHHH	43.79	22817900
430	Phosphorylation	KVDESSESKESEESS HCCCCHHHHHHHHHH	43.61	22817900
433	Phosphorylation	ESSESKESEESSESK CCHHHHHHHHHHHHC	50.86	22817900
436	Phosphorylation	ESKESEESSESKEN- HHHHHHHHHHHCCC-	35.04	22817900
437	Phosphorylation	SKESEESSESKEN-- HHHHHHHHHHCCC--	49.52	18327897
439	Phosphorylation	ESEESSESKEN---- HHHHHHHHCCC----	47.41	27794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BNB_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BNB_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BNB_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RS15B_DROME	RpS15Ab	physical	22036573

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-430; SER-433; SER-436AND SER-437, AND MASS SPECTROMETRY.
PubMed: 18327897