| UniProt ID | BICRA_HUMAN | |
|---|---|---|
| UniProt AC | Q9NZM4 | |
| Protein Name | BRD4-interacting chromatin-remodeling complex-associated protein {ECO:0000305} | |
| Gene Name | BICRA {ECO:0000312|HGNC:HGNC:4332} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1560 | |
| Subcellular Localization | ||
| Protein Description | May play a role in BRD4-mediated gene transcription.. | |
| Protein Sequence | MDDEDGRCLLDVICDPQALNDFLHGSEKLDSDDLLDNPGEAQSAFYEGPGLHVQEASGNHLNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEAEAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGARTLTR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 247 | Phosphorylation | QPVMALNTPTSQLLA CEEEECCCCHHHHHH | 27794612 | ||
| 249 | Phosphorylation | VMALNTPTSQLLAKQ EEECCCCHHHHHHHC | 27794612 | ||
| 250 | Phosphorylation | MALNTPTSQLLAKQV EECCCCHHHHHHHCC | 27794612 | ||
| 260 | O-linked_Glycosylation | LAKQVPVSGYLASAA HHHCCCCCCCHHHHC | 29351928 | ||
| 270 | Phosphorylation | LASAAGPSEPVTLAS HHHHCCCCCCEEEHH | 28348404 | ||
| 274 | Phosphorylation | AGPSEPVTLASAGVS CCCCCCEEEHHCCCC | 27251275 | ||
| 277 | Phosphorylation | SEPVTLASAGVSPQG CCCEEEHHCCCCCCC | 28348404 | ||
| 281 | Phosphorylation | TLASAGVSPQGAGLV EEHHCCCCCCCCCEE | 28348404 | ||
| 349 | Phosphorylation | VILHRTPTPIQPKPA EEEECCCCCCCCCCC | - | ||
| 364 | Phosphorylation | GVLPPKLYQLTPKPF CCCCCHHHCCCCCCC | 17053785 | ||
| 398 | Phosphorylation | PKAPQNLTFMAAGKA CCCCCCEEEEECCCC | 22210691 | ||
| 404 | Methylation | LTFMAAGKAGQNVVL EEEEECCCCCCCEEE | - | ||
| 711 | Ubiquitination | RSQQPLSAEGPHLSV HHCCCCCCCCCCCCC | 22505724 | ||
| 737 | Phosphorylation | AQDPAPATPVAKGAG CCCCCCCCCCCCCCC | 27050516 | ||
| 752 | Phosphorylation | LGPQAPDSQASPAPA CCCCCCCCCCCCCCC | 29255136 | ||
| 755 | Phosphorylation | QAPDSQASPAPAPQI CCCCCCCCCCCCCCC | 29255136 | ||
| 774 | Phosphorylation | PLKGPGPSSSPSLPH CCCCCCCCCCCCCCC | 26074081 | ||
| 775 | Phosphorylation | LKGPGPSSSPSLPHQ CCCCCCCCCCCCCCC | 26074081 | ||
| 776 | Phosphorylation | KGPGPSSSPSLPHQA CCCCCCCCCCCCCCC | 26074081 | ||
| 778 | Phosphorylation | PGPSSSPSLPHQAPL CCCCCCCCCCCCCCC | 26074081 | ||
| 913 | Phosphorylation | FQLQFPPSQGPHKSP CCEECCCCCCCCCCC | 23898821 | ||
| 919 | Phosphorylation | PSQGPHKSPTPPPTL CCCCCCCCCCCCCCC | 29255136 | ||
| 921 | Phosphorylation | QGPHKSPTPPPTLHL CCCCCCCCCCCCCCC | 29255136 | ||
| 925 | Phosphorylation | KSPTPPPTLHLVPEP CCCCCCCCCCCCCCC | 29255136 | ||
| 1012 | Ubiquitination | APSGTPTAPSHAPAP CCCCCCCCCCCCCCC | 22505724 | ||
| 1025 | Ubiquitination | APAPMAATGLPPLLP CCCCCCCCCCCCCCC | 22505724 | ||
| 1040 | Phosphorylation | AENKAFASNLPTLNV CCCHHHHHCCCHHCH | 24719451 | ||
| 1057 | Acetylation | AASSGPGKPSGLQYE HHHCCCCCCCCCCCC | 19608861 | ||
| 1059 | Phosphorylation | SSGPGKPSGLQYESK HCCCCCCCCCCCCHH | 24719451 | ||
| 1063 | Phosphorylation | GKPSGLQYESKLSGL CCCCCCCCCHHHCCC | 24719451 | ||
| 1071 | Ubiquitination | ESKLSGLKKPPTLQP CHHHCCCCCCCCCCC | 22505724 | ||
| 1071 | Acetylation | ESKLSGLKKPPTLQP CHHHCCCCCCCCCCC | 25953088 | ||
| 1072 | Ubiquitination | SKLSGLKKPPTLQPS HHHCCCCCCCCCCCC | - | ||
| 1117 | Phosphorylation | ALHRLLPYHVYQGAL HHHHHHCHHHHCCCC | - | ||
| 1126 | Phosphorylation | VYQGALPSPSDYHKV HHCCCCCCHHHHCCC | 28348404 | ||
| 1130 | Phosphorylation | ALPSPSDYHKVDEEF CCCCHHHHCCCCHHH | - | ||
| 1167 | Phosphorylation | LEESRRVSPSAEMVM HHHHCCCCCCCCEEE | 28348404 | ||
| 1256 | Phosphorylation | RHGGAGGSPSVTWAR ECCCCCCCCCHHHHC | 23401153 | ||
| 1258 | Phosphorylation | GGAGGSPSVTWARAS CCCCCCCCHHHHCCC | 23403867 | ||
| 1260 | Phosphorylation | AGGSPSVTWARASSS CCCCCCHHHHCCCCC | 23403867 | ||
| 1313 | Sumoylation | IGLKLKIKQEAGLSK HCCEEEEEHHHCCCC | - | ||
| 1313 | Sumoylation | IGLKLKIKQEAGLSK HCCEEEEEHHHCCCC | 28112733 | ||
| 1339 | Phosphorylation | QPPPPPATLKVAEPP CCCCCCCCCEECCCC | 26657352 | ||
| 1362 | Phosphorylation | PTGQMNGTVDHPPPA CCCCCCCCCCCCCCC | 22798277 | ||
| 1404 | O-linked_Glycosylation | GPGAPEGTPAGRARG CCCCCCCCCCCCCCC | 29351928 | ||
| 1410 | Methylation | GTPAGRARGGSPAPL CCCCCCCCCCCCCCC | - | ||
| 1413 | Phosphorylation | AGRARGGSPAPLPAK CCCCCCCCCCCCCCC | 25159151 | ||
| 1413 | O-linked_Glycosylation | AGRARGGSPAPLPAK CCCCCCCCCCCCCCC | 29351928 | ||
| 1440 | Phosphorylation | AAVEDELYQRMLKGP HHHHHHHHHHHHHCC | 29978859 | ||
| 1518 | Phosphorylation | LQQAPGRTPAPSYPH HHCCCCCCCCCCCCC | 29449344 | ||
| 1522 | Phosphorylation | PGRTPAPSYPHAASA CCCCCCCCCCCHHHC | 28152594 | ||
| 1523 | Phosphorylation | GRTPAPSYPHAASAG CCCCCCCCCCHHHCC | 28152594 | ||
| 1528 | Phosphorylation | PSYPHAASAGTPASP CCCCCHHHCCCCCCC | 28152594 | ||
| 1531 | Phosphorylation | PHAASAGTPASPPPL CCHHHCCCCCCCCCC | 28152594 | ||
| 1534 | Phosphorylation | ASAGTPASPPPLHRP HHCCCCCCCCCCCCC | 25849741 | ||
| 1544 | Phosphorylation | PLHRPEAYPPSSHNG CCCCCCCCCCCCCCC | 28152594 | ||
| 1547 | Phosphorylation | RPEAYPPSSHNGGLG CCCCCCCCCCCCCCC | 28152594 | ||
| 1548 | Phosphorylation | PEAYPPSSHNGGLGA CCCCCCCCCCCCCCC | 28152594 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BICRA_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BICRA_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BICRA_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| BRD4_HUMAN | BRD4 | physical | 21555454 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
