BICL2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BICL2_HUMAN
• UniProt AC: A1A5D9
• Protein Name: BICD family-like cargo adapter 2
• Gene Name: BICDL2
• Organism: Homo sapiens (Human).
• Sequence Length: 508
• Protein Sequence: MSSPDGPSFPSGPLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLSAQHLEREERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAASLQSELAHSLDDGDQGQGADAPGDTPTTRSPKTRKASSPQPSPPEEILEPPKKRTSLSPAEILEEKEVEVAKLQDEISLQQAELQSLREELQRQKELRAQEDPGEALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSASASSSTPRRAAPRFSLRLGPGPAGGFLSNLFRRT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MSSPDGPSFPSGPLS CCCCCCCCCCCCCCC		28348404
11	Phosphorylation	PDGPSFPSGPLSGGA CCCCCCCCCCCCCCC		27251275
15	Phosphorylation	SFPSGPLSGGASPSG CCCCCCCCCCCCCCC		28348404
19	Phosphorylation	GPLSGGASPSGDEGF CCCCCCCCCCCCCCC		24719451
36	Phosphorylation	FVLERRDSFLGGGPG HHHEECCCCCCCCCC		26657352
151	Phosphorylation	RERARALSELSEQNL HHHHHHHHHHHHHHH		28348404
252	Phosphorylation	RRERREHSLELERAR HHHHHHHHHHHHHHH		23312004
260	Phosphorylation	LELERARSEAGEALS HHHHHHHHHHHHHHH		24114839
267	Phosphorylation	SEAGEALSALRRLQR HHHHHHHHHHHHHHH		24114839
277	Phosphorylation	RRLQRRVSELEEESR HHHHHHHHHHHHHHH		25849741
283	Phosphorylation	VSELEEESRLQDADV HHHHHHHHHHCCCCH		-
318	Phosphorylation	GADAPGDTPTTRSPK CCCCCCCCCCCCCCC		28348404
330	Phosphorylation	SPKTRKASSPQPSPP CCCCCCCCCCCCCCC		26657352
331	Phosphorylation	PKTRKASSPQPSPPE CCCCCCCCCCCCCCH		26657352
335	Phosphorylation	KASSPQPSPPEEILE CCCCCCCCCCHHHCC		26657352
348	Phosphorylation	LEPPKKRTSLSPAEI CCCCCCCCCCCHHHH		25849741
349	Phosphorylation	EPPKKRTSLSPAEIL CCCCCCCCCCHHHHH		25849741
351	Phosphorylation	PKKRTSLSPAEILEE CCCCCCCCHHHHHHH		25849741
425	Phosphorylation	SLQLNRVSLERDSLS HHHHCCHHCCCHHHH		24719451
430	Phosphorylation	RVSLERDSLSRELLR CHHCCCHHHHHHHHH		27251275
432	Phosphorylation	SLERDSLSRELLRAI HCCCHHHHHHHHHHH		27251275
446	Phosphorylation	IRQKVALTQELEAWQ HHHHHHHHHHHHHHH		30622161
473	Phosphorylation	SQRQKELSASASSST HHHHHHHHHCCCCCC		27251275
475	Phosphorylation	RQKELSASASSSTPR HHHHHHHCCCCCCCC		24505115
477	Phosphorylation	KELSASASSSTPRRA HHHHHCCCCCCCCCC		27251275
478	Phosphorylation	ELSASASSSTPRRAA HHHHCCCCCCCCCCC		27251275
479	Phosphorylation	LSASASSSTPRRAAP HHHCCCCCCCCCCCC		27251275
480	Phosphorylation	SASASSSTPRRAAPR HHCCCCCCCCCCCCC		27251275
489	Phosphorylation	RRAAPRFSLRLGPGP CCCCCCEEEECCCCC		27966365

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BICL2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BICL2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BICL2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KLC3_HUMAN	KLC3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.