BGS3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BGS3_SCHPO
• UniProt AC: Q9P377
• Protein Name: 1,3-beta-glucan synthase component bgs3
• Gene Name: bgs3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1826
• Subcellular Localization: Membrane ; Multi-pass membrane protein . Found at the growing tips during interphase and at the septum prior to cytokinesis.
• Protein Description: Required for cell wall biosynthesis and cell elongation..
• Protein Sequence: MDYKKGEHSPSSSIQILSDDATINSNYAYGEQLQSNDQYNNIQHPAPSFANPFIHEQDDSYSDILEEEPDEDAYDSPERPSSTEEFISQDESNISAGSSFMFPYNRGHPLSKRHDSIMVDEFGHEYIVEGDSIASADEAIDYDALYASWTAETKAPILAIDIENIYIELAMKFGFQWDNMRNMFDYLMVMLDSRASRMTPQEALLTLHADYIGGPQSNFKKWYFACKMDQFDLKSGVLSFISRDPSTQVPYKDMSSCEALWISRMDELSNYERIEQLALYLLCWGEANNVRFMPECLCFIYKVAYDYLISPSFKEQKNPAPKDYFLDNCITPLYNLMHDQQYEIRDQKYVRKEKDHASIIGYDDINQMFWYSKGLKALLLSDGSRIMDADVASRYFLLADIQWQRVCYKSFRESRTWLHFLHNFSRIWILHISVFWYFTVYNSPTIYTPNFHYLEGTQPARAAKWCAPALAGAVASFISFLALILEAYFVPRNNPGAQPVIPRLIFVSILIALNIVPAAFIFGFSNATQQHYRSREIVGYVHFFFSIGCVAYQSFIPLPFLLGPRFKFRSSSRKYLANSYFTNDIASLPWGRTLLSAALWITVFIAKFVESYYFLTLSVRDPIRFLQRMKPYDCYDFMIGASLCSHQPKFLLSLVYLTDLVLFFLDTYLWYMLISTMFSIAYSFYMGSAIWTPWRVIFSNLPRRIYFTLLAYKDLSTEFKPKIYVGQIWNSIMISMYREHLLSLEHLKGLLYQQVGSEYFGKQTFQSPKFFMEAAKGLNKWDAFFRRNSEAERRISFFAQSLGGKIPDAVPVPKMPSFTVLIPHYGEKILLSLREIIREQDPMSRITLLEYLKQLYPNDWDNFVQDTKLMAGDVGVEETKSDVKSEKGKKQGTVKEDLPFYCIGFKSTAPEYTLRTRIWASLRSQTLYRTASGMMNYSRALKLLYRVEQPNLLDDCDGNFERLEHQLEQMAYRKFRLCISMQRYAKFNRDEYENAEFLLRAHPELQIAYLDQDPSEDGEEPKVYATLINGFCPFENGRRLPKYRIRLSGNPILGDGKADNQNMALPFVRGEYLQLIDANQDNYIEECMKIRNVLSEFEEMDCATLTPYTKKGNARHPVAMLGAREYVFSENSGILGDVAAGKEQTFGTLFSRSLALIGGKLHYGHPDFLNTIFMTTRGGVSKAQKGLHVNEDIYAGMTALQRGGRIKHCDYFQCGKGRDLGFGTIINFTTKIGTGMGEQSLSREYFYLGTQLPFFRMLSFYYAHAGFHLNNVFIMISMQLLMLVFVNLGAMYHTVEICDYQAGAAINASLYPPGCYMLKPVLDWIRRCIISIFIVFFISFLPLVVHDLLEKGVIRAVARLCKQIFSLSPMFEVFVTQNYANSIFTNLTYGGARYIATGRGLATTRVPFSVLYSLYTGSSIYLGSRLIMMLLFGTMTVWTTHYVYFWVTMFALVICPFIYNPHQFSFVDFFVDYREFLRWLSRGNTKGHAHSWIGFCRLARTRITGVNRKVKGSPSNKLTMDMPRAGLRNVIFTEVFLPACFAFFTICAYTFMNSQPGLEDKSRAVNGFIRIWIMAALPIAISTAALLILLMFSCMLGPLLRKCSKRYGAVLAALAHAVSVFGLVFTFEALWFLEAWSFSKTVLGCIVIFAIHRLVFKLVVVFLLPREVASGENNYSWWDGHWFGRKGIPYMPIQFIREFMCKVVEMNLFAMDFILSHCILFSLTPILCIPFIDIPHSVLLFWLHPSRQIRPPIYTRKQNQLRRRTFYRYSLLFFALLCTFVAMIVVPLVLDQKLSYQFKFENSVKFFRLMQPSLGVLPNTNKNTSE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
235	Phosphorylation	MDQFDLKSGVLSFIS CCCCCCCCCCEEHHC	41.24	25720772
879	Phosphorylation	GDVGVEETKSDVKSE CCCCCCCCHHHHHCC	23.49	21712547
881	Phosphorylation	VGVEETKSDVKSEKG CCCCCCHHHHHCCCC	55.87	24763107
885	Phosphorylation	ETKSDVKSEKGKKQG CCHHHHHCCCCCCCC	44.37	28889911
893	Phosphorylation	EKGKKQGTVKEDLPF CCCCCCCCCCCCCCE	26.38	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BGS3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BGS3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BGS3_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of BGS3_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-885, AND MASSSPECTROMETRY.
PubMed: 18257517