dbPTM

BFSP2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BFSP2_MOUSE
UniProt AC	Q6NVD9
Protein Name	Phakinin {ECO:0000303\|PubMed:21745462}
Gene Name	Bfsp2
Organism	Mus musculus (Mouse).
Sequence Length	416
Subcellular Localization	Cell membrane Peripheral membrane protein Cytoplasmic side . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Detected adjacent to the cell membrane.
Protein Description	Involved in stabilization of lens fiber cell cytoskeleton..
Protein Sequence	MSKRRVAADLPSGTNSSMPVQRHRVSSLRGTHSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLANVPAPGPERDHTTVEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKSSGGWDALRASWASSYQQVGEAVLENARLLLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGFLSRSYEEDVKVLYKQLAGSELEQADVPMGTGLDDVLETIRVQWERDVEKNRAEAGALLQAKQQTEVVHVSQTQEEKLAAALSVELHDTSRQVQSLQAETESLRALKRGLENSLHDAQHWHDMELQNLGAVVGRLEAELAEIRSETEQQQQERAHLLACKSQLQKDVASYHALLDREENN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSKRRVAAD ------CCCCCCCCC	34.56	-
27	Phosphorylation	VQRHRVSSLRGTHSP CCCCCHHHCCCCCCC	21.16	24719451
33	Phosphorylation	SSLRGTHSPSSLDSP HHCCCCCCCHHCCCC	26.73	-
36	Phosphorylation	RGTHSPSSLDSPPAS CCCCCCHHCCCCCCC	39.31	-
91	Phosphorylation	VFLQGLRSSGLANVP HHHHHHHHCCCCCCC	33.53	-
220	Phosphorylation	VIDEANLTKTDLEHQ HHHHHCCCHHHHHHH	31.53	28285833
230	Phosphorylation	DLEHQIESLKEELGF HHHHHHHHHHHHHCC	46.50	28285833
239	Phosphorylation	KEELGFLSRSYEEDV HHHHCCCCCCHHHHH	19.54	25338131
241	Phosphorylation	ELGFLSRSYEEDVKV HHCCCCCCHHHHHHH	33.26	25338131
242	Phosphorylation	LGFLSRSYEEDVKVL HCCCCCCHHHHHHHH	23.40	25338131
336	Phosphorylation	VQSLQAETESLRALK HHHHHHHHHHHHHHH	33.61	-
338	Phosphorylation	SLQAETESLRALKRG HHHHHHHHHHHHHHH	30.49	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BFSP2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BFSP2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BFSP2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BFSP2_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BFSP2_MOUSE

Related Literatures of Post-Translational Modification