BFR2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BFR2_SCHPO
• UniProt AC: Q9US05
• Protein Name: Protein bfr2
• Gene Name: bfr2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 452
• Subcellular Localization: Nucleus, nucleolus.
• Protein Sequence: MGKVSLKDELAGMLNPQPQERDPEALEDAFSDREDSSEEENDTLGREHYVDVSESKLRSKQAPQLDPKFKGRKTSRQELLNSGSLNSQSSSPSEEEDSEEDENDAVSEDHENFSSSEASSISEENEDDDQSSAIPEKDMDRLKKIINGEKKLSDQIRTSALEDMKKGLALKEQMRFYDNVLDTRIRLQKGCSQLLSSSNQLQGDKVEARDGLVSFIQHTLQLRKNLLIDSGVEILDSRSKRKENPVSLEEIALEMNNLDDSLNEWKNDTLTKWHNRVQAVQGISQSNKFKALNQSIVQQIENSMINKKDLVERTRIDYSDPNNKTFNPEIYNDTDFYQSLLKDFINSRMADSTRDGTVRWMATKKQKQKKENVDTKASKGRKIRYHVHDKLQNFMAPIEVTVWPDEQTEDLFSSLLGQQLDLSETANDTNTSNFVEKDDELISSNDGFSLFG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Phosphorylation	EALEDAFSDREDSSE HHHHHHHHCCCCCCH	37.16	28889911
36	Phosphorylation	AFSDREDSSEEENDT HHHCCCCCCHHHHHC	34.59	28889911
37	Phosphorylation	FSDREDSSEEENDTL HHCCCCCCHHHHHCC	62.44	28889911
43	Phosphorylation	SSEEENDTLGREHYV CCHHHHHCCCCHHEE	42.57	28889911
443	Phosphorylation	EKDDELISSNDGFSL CCCCHHHCCCCCCCC	35.40	21712547
444	Phosphorylation	KDDELISSNDGFSLF CCCHHHCCCCCCCCC	31.76	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BFR2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BFR2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BFR2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of BFR2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-31; SER-36 AND SER-37,AND MASS SPECTROMETRY.
PubMed: 18257517