BEGIN_RAT - dbPTM
BEGIN_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BEGIN_RAT
UniProt AC O88881
Protein Name Brain-enriched guanylate kinase-associated protein
Gene Name Begain
Organism Rattus norvegicus (Rat).
Sequence Length 611
Subcellular Localization Cytoplasm. Membrane
Peripheral membrane protein.
Protein Description May sustain the structure of the postsynaptic density (PSD)..
Protein Sequence MWTGGRRPGRLRRAASAADMEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELDKVTEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRAMSHEIVALNSHLLEAKVTIDKLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQQRVSLHMEKHGCSLPSPLCHPSYADSVPTCVIAKVLEKPDPGSLSSRMSDASARDLAYRDGVENPGPRPPYKGDIYCSDTALYCPDERDHDRRPSVDTPVTDVGFLRAQNSTDSLAEEEEAEAAAFPEAYRREAFQGYAASLPTSSSYSSFSATSEEKEHAQASTLTASQQAIYLNSREELFSRKPPSATYGSSPRYAKAAATLGSPLEAQVAPGFARTVSPYPAEPYRYPASQQALMPPNLWSLRAKPSGNRLAAREDIRGQWRPLSVEDVGAYSYQAGAAGRAASPCNFSERFYGGGGGGGSPGKNAEGRASPLYASYKADSFSEGDDLSQGHLAEPCFLRAGGDLSLSPSRSADPLPGYATSDGDGDRLGVQLCGPGSSPEPEHGSRDSLEPSSMEASPEMHPPTRLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
16PhosphorylationGRLRRAASAADMEKL
HHHHHHHHHHCHHHH		24.0125403869
39PhosphorylationELRKRLSYTTHKLEK
HHHHHHHHHHHHHHH		21.90-
46UbiquitinationYTTHKLEKLETEFDS
HHHHHHHHHHCHHHH		63.16-
139PhosphorylationLSEDNELYRKDCNLA
HHHCCHHHHHHCHHH		14.94-
155PhosphorylationQLLQCSQTYGRVHKV
HHHHHHHHHCCCEEH		16.20-
156PhosphorylationLLQCSQTYGRVHKVS
HHHHHHHHCCCEEHH		8.69-
219PhosphorylationGSLSSRMSDASARDL
CCHHHHCCCHHHHHH		28.99-
228PhosphorylationASARDLAYRDGVENP
HHHHHHHHHCCCCCC		19.28-
246PhosphorylationPPYKGDIYCSDTALY
CCCCCCEEECCCCEE		7.22-
248PhosphorylationYKGDIYCSDTALYCP
CCCCEEECCCCEECC		22.48-
253PhosphorylationYCSDTALYCPDERDH
EECCCCEECCCCCCC		10.24-
265PhosphorylationRDHDRRPSVDTPVTD
CCCCCCCCCCCCCCH		30.7128551015
268PhosphorylationDRRPSVDTPVTDVGF
CCCCCCCCCCCHHHH		19.9428551015
281PhosphorylationGFLRAQNSTDSLAEE
HHHCCCCCCCCHHHH		22.8522673903
282PhosphorylationFLRAQNSTDSLAEEE
HHCCCCCCCCHHHHH		36.8422673903
284PhosphorylationRAQNSTDSLAEEEEA
CCCCCCCCHHHHHHH		29.5722673903
358PhosphorylationLFSRKPPSATYGSSP
HHHCCCCCCCCCCCH		41.59-
360PhosphorylationSRKPPSATYGSSPRY
HCCCCCCCCCCCHHH		32.52-
361PhosphorylationRKPPSATYGSSPRYA
CCCCCCCCCCCHHHH		18.09-
363PhosphorylationPPSATYGSSPRYAKA
CCCCCCCCCHHHHHH		27.10-
364PhosphorylationPSATYGSSPRYAKAA
CCCCCCCCHHHHHHH		14.72-
373PhosphorylationRYAKAAATLGSPLEA
HHHHHHHHHCCCHHH		27.2522673903
376PhosphorylationKAAATLGSPLEAQVA
HHHHHHCCCHHHHCC		29.4422673903
391PhosphorylationPGFARTVSPYPAEPY
CCCCCCCCCCCCCCC		20.36-
399MethylationPYPAEPYRYPASQQA
CCCCCCCCCCHHHCC		41.49-
399Asymmetric dimethylargininePYPAEPYRYPASQQA
CCCCCCCCCCHHHCC		41.49-
438PhosphorylationRGQWRPLSVEDVGAY
CCCCCCCCHHHHCCE		26.58-
445PhosphorylationSVEDVGAYSYQAGAA
CHHHHCCEEECCCCC		11.28-
447PhosphorylationEDVGAYSYQAGAAGR
HHHCCEEECCCCCCC		6.95-
474PhosphorylationGGGGGGGSPGKNAEG
CCCCCCCCCCCCCCC		33.4830411139
484PhosphorylationKNAEGRASPLYASYK
CCCCCCCCCCCCCCC		17.6825403869
487PhosphorylationEGRASPLYASYKADS
CCCCCCCCCCCCCCC		9.26-
489PhosphorylationRASPLYASYKADSFS
CCCCCCCCCCCCCCC		17.38-
490PhosphorylationASPLYASYKADSFSE
CCCCCCCCCCCCCCC		11.30-
494PhosphorylationYASYKADSFSEGDDL
CCCCCCCCCCCCCCC		35.2228551015
496PhosphorylationSYKADSFSEGDDLSQ
CCCCCCCCCCCCCCC		44.6228551015
502PhosphorylationFSEGDDLSQGHLAEP
CCCCCCCCCCCCCCC		40.9028551015
519PhosphorylationLRAGGDLSLSPSRSA
EECCCCCCCCCCCCC		31.3827097102
521PhosphorylationAGGDLSLSPSRSADP
CCCCCCCCCCCCCCC		19.9030411139
523PhosphorylationGDLSLSPSRSADPLP
CCCCCCCCCCCCCCC		35.1823984901
525PhosphorylationLSLSPSRSADPLPGY
CCCCCCCCCCCCCCC		41.16-
551PhosphorylationVQLCGPGSSPEPEHG
EEEECCCCCCCCCCC		45.9428551015
552PhosphorylationQLCGPGSSPEPEHGS
EEECCCCCCCCCCCC		38.9228551015
571PhosphorylationEPSSMEASPEMHPPT
CCCCCCCCCCCCCCC		14.21-
578PhosphorylationSPEMHPPTRLSPQQA
CCCCCCCCCCCHHHC		49.0125403869
581PhosphorylationMHPPTRLSPQQAFPR
CCCCCCCCHHHCCCC		19.8525403869
599PhosphorylationSGLSRKDSLTKAQLY
CCCCCHHHCCHHHHH		40.76-
606PhosphorylationSLTKAQLYGTLLN--
HCCHHHHHHHHCC--		8.9325403869
608PhosphorylationTKAQLYGTLLN----
CHHHHHHHHCC----		17.9522673903
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BEGIN_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BEGIN_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BEGIN_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of BEGIN_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BEGIN_RAT

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Related Literatures of Post-Translational Modification

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