BDP1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BDP1_MOUSE
• UniProt AC: Q571C7
• Protein Name: Transcription factor TFIIIB component B'' homolog
• Gene Name: Bdp1
• Organism: Mus musculus (Mouse).
• Sequence Length: 2467
• Subcellular Localization: Nucleus.
• Protein Description: General activator of RNA polymerase III transcription. Requires for transcription from all three types of polymerase III promoters. Requires for transcription of genes with internal promoter elements and with promoter elements upstream of the initiation site (By similarity)..
• Protein Sequence: MFRRARLSVKPNVRPGVGTRGSAAPNPQRGPEAPRPPEPATESAPKPAEPTDVPAVDSGGAEPQEQAPGSSDEKTGDKNNAAESSTLSSASSQRRKRVSSTSSLVQPSGSAPSQSRPLSTVDHDAPQPNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEKKQWKNKFSTNESQRPPDRSKMTMRDFIYYLPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDANDNEDVEEEVDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSLKEKASKPRKNLKAKTVTSEEVNDDPDESVNSNISDPERSQNDAETVNEEESPSSSGQHLEQAMLEQDQNQEKKRRRNQGEANKQEATNLLERVLVHSSPPAAEIHKNTCPSEENESECNKEQIPSLTQNIDDIAGLAPSEETEMRMDPIPSTCNQQDIMPLARESSESCAVALPVWEPGNTASADMAHAESSCSEGRGADLKTAAPETEQTENVKPKSRSRLQRPKPNLARAVGKKSAVSQDRQDERNKNSPSETAAEKNHMEKETMNESETSVAKNTDGESPGAKTVSDLSEKSCVQQDSQAKVLRPTRLMRSRMQRPKPNVVKAAERKEILTSQEKFGAHVEKSEDESCVVIPPQTENESHKNLQCEDTVSEPGRKDPFENIQPDQPQVLSDCPSIHEGNKENKRKQVPVLRTRFQKPKPNTGRRRRRISSKEGIPEETPISGEIPATWEEIPSLDTSLREEVLSVPLAPLTATASTKDSESDVKDSGRNDTASNAEMSEMTDVTMEMETGLETIGRDTCPGEMGAEMIDIPMETEAGLKASLNETSCMEKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVGPVSEPETGLQETGKDLAMKESTPDTTDSTEEREAYSEETERQEKISALIKDAEEAKARGEMETPLEEIGGGTSQRGKAAGAPVEQSASEEEPQGSACREEVAVESSTAEGKELNLRETGEDDVSSMVVVLGEKTDIEETNGDPKETERESSVSWERGSGEIQVGEEMVEDLGKPEKIDVAPREREPEEHSSGQPEADVILSSSDGSTGSPQDKVNISSKISVMPTLVEEKETTDKDISSHLGHVESCSQNLGRHETDQGMPLPDALERFSDTNLSKPLPQEQQPLQVKPAPFLRSRFKKPKPNLSRAALKRATIEAEHCVPGKKSEACKVEAAMLQQDSDQAALSPQHNVPSLMASRENDKSGHEEEEEAAILPCTQTEKDASPPNSSEPKEGSQLTPNQENGLLVPIGTPMMNTVTQETRQNVVQTTLPVRGRLQRPRPNVQKARQRQIVEKGEARDIAKNEGPELQKDETRTCLTVANSSHIESGVAVDMSSRVSECQVSESQGHADPVENLSVNKASVVHEQMRHENKPYVPSPALLIRRRFQKAKPNLGGARRKDEQPGVEKGRTDESTALTAEDHLLQKEDCDTQLSLQAREKADMPLEVSVRKECIHSEESGSDRNDAQPNAGPSEGSRDETAKEQPTSLGLEEQSLSKQIRSSCPQLWKESSYPKTVSSRRTPLSSASECEIEHSWKRTQRKTKPNLTKGRGSKRIRGKTAKKEPRASKSVLVTLRASQKEDEDDAEDFDSDYEEETYHLAPEELSKAPVFVPVGLRSPEPVSAQIEETMEELEITMDVADMTVVEHQLSHMDTTAQAVQAEKAVYPPSFEMDVGEQTQEEPGPSDGSTEAAITLLTMGDIVLQSEIIPGQGDVGVCVFPDVHSEDKSHAPFSPDNVNQKVVHDYPEVCSPVISTSHASFEENRIVSKEQSNRDAAVEEEAVEETLPTRNTTSTMSTHLRMESMVVTPELNSEKTLEISESHGHQEVASFCITKETEVEIQRETEGDDSKAVELEDKSHAPVTAAETKEEEQSQCVGDVEGASVSQEAILPARIEDHEETLQEVQESGTAVASSEIGQQTLDSGQSFGESAAKEALKETPKGSDVPVLHGPESVPSHIPEAQQENTGPQAVTVNPFADGQQDGEDEQAFILTLVEIPTHATEGFTDAAMQLMPSSLLPAPILVRSGNAAERGDLSGSLQTSLVVQDAPSLSPSRSGSSEKPPANLDLTSRKRFCCSPDESIHVPPAKKSSLVPGIDYQECTSEVCSEELNVFEKTAESCMGQGIFPTSESTHATSKPQKEHSEPTDTGSSGSLDEIKDACVENMAQLPQSEIVSDKEEKTEPASNSEQRDIVTSSSKPPLTRPGRRPLGFLSLLCPKNSLESDEVTQTHSKKRLKPQIPVSRRNLRKPNLHNTSQKKNQDSSAPPPSPSVTAPLSGTAGSPESSAAQVSSDQPLLKEECKNGPKGAPEEEVTPVSEFVFSDIFIEVDETL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
99	Phosphorylation	SQRRKRVSSTSSLVQ HHHHHHCCCCCCCCC	31.75	25338131
101	Phosphorylation	RRKRVSSTSSLVQPS HHHHCCCCCCCCCCC	18.15	28576409
131	Phosphorylation	DAPQPNPTPAKEKQP CCCCCCCCCCCCCCC	42.38	28066266
212	Phosphorylation	QEKKPEKSLAPTPTR HCCCCCCCCCCCCCC	28.27	25521595
287	Methylation	ENDPIFERGSTTTYS CCCCCCCCCCCCCCH	33.34	30989515
295	Phosphorylation	GSTTTYSSFRKNYYS CCCCCCHHHHHHCCC	20.75	28576409
297	Methylation	TTTYSSFRKNYYSKP CCCCHHHHHHCCCCC	28.40	30989521
490	Phosphorylation	LERVLVHSSPPAAEI HHHHHHCCCCCHHHH	36.74	26745281
491	Phosphorylation	ERVLVHSSPPAAEIH HHHHHCCCCCHHHHH	21.74	25266776
644	Phosphorylation	QDERNKNSPSETAAE HHHHHCCCHHHHHHH	31.26	27841257
723	Acetylation	VVKAAERKEILTSQE CHHHHHHHHHHHCHH	40.38	19859133
894	Phosphorylation	TASNAEMSEMTDVTM CCCHHHHHHHHHCEE	18.74	-
1001	Phosphorylation	KDLAMKESTPDTTDS CCHHHCCCCCCCCCC	39.46	22871156
1002	Phosphorylation	DLAMKESTPDTTDST CHHHCCCCCCCCCCH	26.69	22871156
1005	Phosphorylation	MKESTPDTTDSTEER HCCCCCCCCCCHHHH	33.43	22871156
1285	Phosphorylation	KKPKPNLSRAALKRA CCCCCCCCHHHHHHH	26.89	22942356
1634	Phosphorylation	GLEEQSLSKQIRSSC CCCHHHHHHHHHHHC	27.97	28059163
1715	Phosphorylation	VLVTLRASQKEDEDD EEEEEEHHHCCCCCC	35.04	23984901
1728	Phosphorylation	DDAEDFDSDYEEETY CCHHHCCCCHHHHHH	41.93	21149613
1730	Phosphorylation	AEDFDSDYEEETYHL HHHCCCCHHHHHHCC	29.23	23984901
1734	Phosphorylation	DSDYEEETYHLAPEE CCCHHHHHHCCCHHH	21.37	23984901
1735	Phosphorylation	SDYEEETYHLAPEEL CCHHHHHHCCCHHHH	9.71	23984901
1743	Phosphorylation	HLAPEELSKAPVFVP CCCHHHHHCCCEEEE	30.01	30635358
1865	Phosphorylation	DVHSEDKSHAPFSPD CCCCCCCCCCCCCCC	36.88	29472430
1870	Phosphorylation	DKSHAPFSPDNVNQK CCCCCCCCCCCCCCC	30.22	25521595
1882	Phosphorylation	NQKVVHDYPEVCSPV CCCEECCCHHHCCCE	6.09	26745281
1887	Phosphorylation	HDYPEVCSPVISTSH CCCHHHCCCEECCCC	27.64	26745281
1940	Phosphorylation	STHLRMESMVVTPEL CHHEEEEEEEECCCC	13.92	-
1952	Phosphorylation	PELNSEKTLEISESH CCCCCCCEEEEEHHH	26.10	-
2186	Phosphorylation	LVVQDAPSLSPSRSG EEEEECCCCCCCCCC	43.11	21743459
2188	Phosphorylation	VQDAPSLSPSRSGSS EEECCCCCCCCCCCC	25.76	21743459
2378	Phosphorylation	LKPQIPVSRRNLRKP CCCCCCCCHHCCCCC	21.84	30482847
2408	Phosphorylation	PPPSPSVTAPLSGTA CCCCCCCCCCCCCCC	27.22	25521595
2412	Phosphorylation	PSVTAPLSGTAGSPE CCCCCCCCCCCCCCC	32.79	25521595
2417	Phosphorylation	PLSGTAGSPESSAAQ CCCCCCCCCCCHHCC	24.03	25521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BDP1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BDP1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BDP1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of BDP1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.