dbPTM

BCD1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BCD1_SCHPO
UniProt AC	O74906
Protein Name	Putative box C/D snoRNA protein SPCC613.07
Gene Name	SPCC613.07
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	345
Subcellular Localization	Nucleus .
Protein Description	Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis..
Protein Sequence	MSENRLGICSTCQKNASKYRCPRCDSRFCCLECNLEHKRLTKCSGERDPATFVPKSKLVNHLNSDFNFLSGVERLINRKENGSHQVSNRAERNRLQLKRSLERAGINIKFAPPSNKKRRLNRTHYDKKSHLIKWSIEWCLHESSTSKDLTDEASENTIITHSHPESEPLEKIFRKLVEENSEMNSQVSKANIHAPDDMQFMIKSRKSRSKGFIYKKIEPSNSLSSCLRNSFVFEVPTIHVFTSTTQVHTESSYETSSSEQSDDSSSSSSCISDSEESSSDDELNELSNEKKANSPTQNVDTSSKLSSVKFQNEDDEDRRKNSDGSEASYSLPPLFGSYFQKQGQY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
294	Phosphorylation	SNEKKANSPTQNVDT HHHHHCCCCCCCCCC	33.90	28889911
296	Phosphorylation	EKKANSPTQNVDTSS HHHCCCCCCCCCCCH	32.37	28889911
322	Phosphorylation	DEDRRKNSDGSEASY HHHHHHCCCCCHHHH	46.51	21712547
325	Phosphorylation	RRKNSDGSEASYSLP HHHCCCCCHHHHCCC	34.67	25720772
328	Phosphorylation	NSDGSEASYSLPPLF CCCCCHHHHCCCCCH	15.94	25720772
329	Phosphorylation	SDGSEASYSLPPLFG CCCCHHHHCCCCCHH	22.67	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BCD1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BCD1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BCD1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BCD1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BCD1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-294 AND THR-296, ANDMASS SPECTROMETRY.	18257517 [Abstract]