dbPTM

BCAT1_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BCAT1_RAT
UniProt AC	P54690
Protein Name	Branched-chain-amino-acid aminotransferase, cytosolic
Gene Name	Bcat1
Organism	Rattus norvegicus (Rat).
Sequence Length	411
Subcellular Localization	Cytoplasm.
Protein Description	Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine..
Protein Sequence	MAYLSRATATLARQDCSNGCSASYAEEEELEASTESYDEEGGSEASTQTFRAKDLIITKADVLKKKPDPSSLVFGASFTDHMLMVEWTSKYGWDKPHIKPFENLSIHPAASVLHYAVELFEGLKAFRGVDNKIRLFRPDLNMKRMCRSAVRTTLPEFDKEELLQCVLQLIQLDREWVPYSTSASLYIRPTFIGIEPSLGVKKPSKALLFVILSPVGSYFSNGTFSPVSLWANPKFVRSWKGGTGDFKMGCNYGSSLLAQCEAAENGCHQVLWLYGKENRITEVGTMNLFLYWINKDGEEELATPPLDGVILPGVTRQSILELGEEWGEFKVCERHITMDDLSTALEENRVKEMFGSGTACVVCPVASILYKGQMLHIPTMENGHKLSSRIMAKLTDIQYGRIKSEWTLELP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
53	Ubiquitination	STQTFRAKDLIITKA CCCCEEHHHEEEEHH	49.13	-
59	Acetylation	AKDLIITKADVLKKK HHHEEEEHHHHHHCC	31.98	22902405
59	Ubiquitination	AKDLIITKADVLKKK HHHEEEEHHHHHHCC	31.98	-
143	Ubiquitination	FRPDLNMKRMCRSAV CCCCCCHHHHHHHHH	35.59	-
240	Acetylation	PKFVRSWKGGTGDFK HHHHEECCCCCCCCC	49.02	22902405
240	Ubiquitination	PKFVRSWKGGTGDFK HHHHEECCCCCCCCC	49.02	-
247	N6-(pyridoxal phosphate)lysine	KGGTGDFKMGCNYGS CCCCCCCCCCCCCCH	38.84	-
247	Other	KGGTGDFKMGCNYGS CCCCCCCCCCCCCCH	38.84	-
393	Acetylation	LSSRIMAKLTDIQYG HHHHHHHHCCCCCCC	34.24	22902405
393	Ubiquitination	LSSRIMAKLTDIQYG HHHHHHHHCCCCCCC	34.24	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BCAT1_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BCAT1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BCAT1_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BCAT1_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BCAT1_RAT

Related Literatures of Post-Translational Modification