dbPTM

BASP1_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BASP1_RAT
UniProt AC	Q05175
Protein Name	Brain acid soluble protein 1
Gene Name	Basp1
Organism	Rattus norvegicus (Rat).
Sequence Length	220
Subcellular Localization	Cell membrane Lipid-anchor. Cell projection, growth cone. Associated with the membranes of growth cones that form the tips of elongating axons.
Protein Description
Protein Sequence	MGSKLSKKKKGYNVNDEKAKDKDKKAEGAGTEEEGTQKESEPQAAADATEVKESAEEKPKDAADGEAKAEEKEADKAAAKEEAPKAEPEKSEGAAEEQPEPAPAPEQEAAAPGPAAGGEAPKAGEASAESTGAADGAPQEEGEAKKTEAPAAGPEAKSDAAPAASDSKPSTEPAPSSKETPAASEAPSSAAKAPAPAAPAAEPQAEAPVASSEQSVAVKE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	N-myristoyl glycine	------MGSKLSKKK ------CCCCHHHCC	33.22	-
2	Myristoylation	------MGSKLSKKK ------CCCCHHHCC	33.22	8193160
18	Ubiquitination	GYNVNDEKAKDKDKK CCCCCHHHHHHHHHH	64.70	-
25	Ubiquitination	KAKDKDKKAEGAGTE HHHHHHHHCCCCCCC	62.90	-
31	Phosphorylation	KKAEGAGTEEEGTQK HHCCCCCCCCCCCCC	39.42	30411139
36	Phosphorylation	AGTEEEGTQKESEPQ CCCCCCCCCCCCCCC	39.48	28432305
38	Ubiquitination	TEEEGTQKESEPQAA CCCCCCCCCCCCCHH	64.15	-
40	Phosphorylation	EEGTQKESEPQAAAD CCCCCCCCCCCHHHH	62.71	28432305
49	Phosphorylation	PQAAADATEVKESAE CCHHHHHHHHHHHHH	41.69	25403869
52	Ubiquitination	AADATEVKESAEEKP HHHHHHHHHHHHHCC	39.45	-
54	Phosphorylation	DATEVKESAEEKPKD HHHHHHHHHHHCCCC	34.95	28432305
58	Ubiquitination	VKESAEEKPKDAADG HHHHHHHCCCCCCCC	49.20	-
58	Acetylation	VKESAEEKPKDAADG HHHHHHHCCCCCCCC	49.20	22902405
60	Ubiquitination	ESAEEKPKDAADGEA HHHHHCCCCCCCCHH	71.69	-
68	Ubiquitination	DAADGEAKAEEKEAD CCCCCHHHHHHHHHH	52.62	-
72	Ubiquitination	GEAKAEEKEADKAAA CHHHHHHHHHHHHHH	50.11	-
80	Ubiquitination	EADKAAAKEEAPKAE HHHHHHHHHHCCCCC	51.89	-
85	Acetylation	AAKEEAPKAEPEKSE HHHHHCCCCCCCCCC	72.87	22902405
85	Ubiquitination	AAKEEAPKAEPEKSE HHHHHCCCCCCCCCC	72.87	-
90	Ubiquitination	APKAEPEKSEGAAEE CCCCCCCCCCCCCCC	65.60	-
90	Acetylation	APKAEPEKSEGAAEE CCCCCCCCCCCCCCC	65.60	22902405
91	Phosphorylation	PKAEPEKSEGAAEEQ CCCCCCCCCCCCCCC	39.33	23712012
127	Phosphorylation	APKAGEASAESTGAA CCCCCCCCHHHCCCC	28.41	30240740
130	Phosphorylation	AGEASAESTGAADGA CCCCCHHHCCCCCCC	31.68	23589303
131	Phosphorylation	GEASAESTGAADGAP CCCCHHHCCCCCCCC	23.50	25403869
146	Ubiquitination	QEEGEAKKTEAPAAG HHCCCCCCCCCCCCC	59.66	-
158	Phosphorylation	AAGPEAKSDAAPAAS CCCCCCCCCCCCCCC	39.26	-
165	Phosphorylation	SDAAPAASDSKPSTE CCCCCCCCCCCCCCC	44.52	-
167	Phosphorylation	AAPAASDSKPSTEPA CCCCCCCCCCCCCCC	43.93	-
170	Phosphorylation	AASDSKPSTEPAPSS CCCCCCCCCCCCCCC	49.49	-
184	Phosphorylation	SKETPAASEAPSSAA CCCCCCHHHCCCHHH	36.08	28432305
188	Phosphorylation	PAASEAPSSAAKAPA CCHHHCCCHHHCCCC	39.39	25403869
189	Phosphorylation	AASEAPSSAAKAPAP CHHHCCCHHHCCCCC	31.05	30240740
211	Phosphorylation	QAEAPVASSEQSVAV CCCCCCCCCCCCCCC	34.34	28432305
212	Phosphorylation	AEAPVASSEQSVAVK CCCCCCCCCCCCCCC	29.89	28432305
215	Phosphorylation	PVASSEQSVAVKE-- CCCCCCCCCCCCC--	14.16	28432305
219	Acetylation	SEQSVAVKE------ CCCCCCCCC------	48.22	22902405
219	Ubiquitination	SEQSVAVKE------ CCCCCCCCC------	48.22	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BASP1_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BASP1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BASP1_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BASP1_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BASP1_RAT

Related Literatures of Post-Translational Modification

Myristoylation
Reference	PubMed
"Expression and myristoylation of NAP-22 using a baculovirus transfervector system."; Maekawa S., Matsuura Y., Nakaruma S.; Biochim. Biophys. Acta 1218:119-122(1994). Cited for: MYRISTOYLATION AT GLY-2.	8193160 [Abstract]