BARH2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BARH2_HUMAN
• UniProt AC: Q9NY43
• Protein Name: BarH-like 2 homeobox protein
• Gene Name: BARHL2
• Organism: Homo sapiens (Human).
• Sequence Length: 387
• Subcellular Localization: Nucleus .
• Protein Description: Potential regulator of neural basic helix-loop-helix genes..
• Protein Sequence: MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQPPPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSSPIPGTPHPR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
139	Phosphorylation	ASAPRTSTSSFLIKD CCCCCCCCCCCHHHH	27.98	30576142
140	Phosphorylation	SAPRTSTSSFLIKDI CCCCCCCCCCHHHHH	20.89	30576142
151	Phosphorylation	IKDILGDSKPLAACA HHHHHCCCCCCCEEC	34.08	24719451
354	Methylation	APHPQLQRPLVPRVL CCCCCCCCCCCCEEE	34.80	-
359	Methylation	LQRPLVPRVLIHGLG CCCCCCCEEEEECCC	28.52	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BARH2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BARH2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BARH2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of BARH2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.