dbPTM

ATU2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ATU2_SCHPO
UniProt AC	O59666
Protein Name	Copper-transporting ATPase ccc2
Gene Name	ccc2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	904
Subcellular Localization	Golgi apparatus, trans-Golgi network membrane Multi-pass membrane protein .
Protein Description	Probably involved in copper transport and in the regulation of cellular copper level. Retrieves copper from the metallochaperone atx1 and incorporates it into trans-Golgi vesicles (By similarity)..
Protein Sequence	MYTTTLSVQGMTCTSCVASIQSMLEGVEGIEQFTISLLLERAIAVHDPSIISPDQIAEKIEDCGFDASVISSTEGEHGVMANYLLLSPMQAEQWTKVHNHINELQGVLSVNCSSSPDAAIRVIYDSEITGPRSIMKEILSMGVKCTFQPVDSSTSRILSLQRGSQIRVWKIRFIISISFSLAVMFLPQIFDSCDSMRAAFLVPHYFGICAGHIISLVLSLPVQFGVGRVYYSAAYHALKRGTANMDVLVSLGSTVAFAASIFFMILYSARHADNPAPIFFDTADMLLTFVTLGRYLESKAKGSTSAALSQLLSLAPSSATIIEDNEQIEILADLIERGDLILVKPGEIIPVDGTVVEGSSYVDESSVSGEPVPVHKTIDDELLSGTANGNGRLLVKATKSPRESQLAVIVDLVQRAQISHAPIQQFADRVAGIFVPVIVALSISTFTFWFLFTKYSSKYPSVFDDPMGKFAVCLKLTISVVVVACPCALGLSTPTAVMVGTGVGALNGIIIKGGEILERLNQVDTVVFDKTGTLTVGKLSVTDISIVDNLEELLDIPKNIFWAFVKASESSSEHPIGKAITEKASEFTDVSEIGIESFNAVPGEGVDVVLRWKERTFHALLGNSLLLEHNNVSIPDDFDSKLKLSSSSGLTCVRIAIDGQFVGFLGCMDQVRPDSYQTVSALKQLGKKVCLLTGDQKATARRVAQGLEIDFSDVYAEAVPSQKAEIIQKLKDQKHCVAMVGDGINDSPSLVLADVGIAPINGSGIALESADVILVRKGVLLDTAVSFDLSRVIVKRIKMNLVWACIYNFVMIPIAMGFFLPWGIYLNPMWASAAMMFSSLSVLASSLLLRRWKKPKSLIFSEADDVETESSTNSSVLQKVYTATRSIFGRNKSSNKYQPVANEV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
870	Phosphorylation	ADDVETESSTNSSVL CCCCCCCCCCCHHHH	50.29	25720772
871	Phosphorylation	DDVETESSTNSSVLQ CCCCCCCCCCHHHHH	25.94	25720772
882	Phosphorylation	SVLQKVYTATRSIFG HHHHHHHHHHHHHHC	25.25	21712547
884	Phosphorylation	LQKVYTATRSIFGRN HHHHHHHHHHHHCCC	19.70	21712547
886	Phosphorylation	KVYTATRSIFGRNKS HHHHHHHHHHCCCCC	20.22	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ATU2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ATU2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ATU2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ATU2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ATU2_SCHPO

Related Literatures of Post-Translational Modification