ATS15_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATS15_MOUSE
• UniProt AC: P59384
• Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 15
• Gene Name: Adamts15
• Organism: Mus musculus (Mouse).
• Sequence Length: 950
• Subcellular Localization: Secreted, extracellular space, extracellular matrix.
• Protein Sequence: MLLLGISILALAWRPAGSSEPEWEVVVPIRRDPDINGRHYYRRGTEDSGDQGLIFQITAFQQDFYLHLTPDAQFLAPAFATEYLGVPLQRLTGSSLDLRRCFYSGYVNAEPDSFAAVSLCGGLRGAFGYRGAEYVISPLPNTSAPEAQRHSQGAHLLQRRGAPVGPSGDPTSRCGVASGWNPAILRALDPYKPRRTGAGESHNRRRSGRAKRFVSIPRYVETLVVADESMVKFHGADLEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLGDRDTGPKVTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNMPHDNVKVCEEVFGKLRANHMMSPTLIQIDRANPWSACSAAIITDFLDSGHGDCLLDQPSKPITLPEDLPGTSYSLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQMVCQTRHFPWADGTSCGEGKFCLKGACVERHNPNKYRVDGSWAKWEPYGSCSRTCGGGVQLARRQCSNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYVLAPKVVDGTLCTPDSTSVCVQGKCIKAGCDGNLGSKKKFDKCGVCGGDNKSCKRVTGLFTKPMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSVLRYSGTGTAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSTRPKDPRGSPVLRNSVLSLSNQVEQPDNRPPARWVAGSWGPCSVSCGSGLQKRAVDCRDSPGQQGASACDVDHRPLEKRACGEPCPTWELGNWSPCSKSCGRGFKRRPLKCVGHGGRLLARDQCDLRRKPQELDFCVLRPC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
141	N-linked_Glycosylation	YVISPLPNTSAPEAQ EEEECCCCCCCCHHH	55.11	24220035
591	N-linked_Glycosylation	CEAFNGYNHSTNRLT HHHHCCCCCCCCCEE	24.83	-
608	Phosphorylation	VAWVPKYSGVSPRDK EEECCCCCCCCHHHH	38.55	51458301
623	N-linked_Glycosylation	CKLICRANGTGYFYV CEEEEECCCCEEEEE	29.25	-
679	N-linked_Glycosylation	CGVCGGDNKSCKRVT CCCCCCCCCCCCCCC	41.22	-
760	Phosphorylation	KGSVLRYSGTGTAVE ECEEEEEECCCHHHH	24.36	29895711
762	Phosphorylation	SVLRYSGTGTAVESL EEEEEECCCHHHHHH	25.97	29895711
764	Phosphorylation	LRYSGTGTAVESLQA EEEECCCHHHHHHHH	27.63	29895711

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ATS15_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATS15_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATS15_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ATS15_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.