ATRN1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATRN1_MOUSE
• UniProt AC: Q6A051
• Protein Name: Attractin-like protein 1
• Gene Name: Atrnl1
• Organism: Mus musculus (Mouse).
• Sequence Length: 1378
• Subcellular Localization: Cell membrane ; Single-pass membrane protein .
• Protein Description: May play a role in melanocortin signaling pathways that regulate energy homeostasis..
• Protein Sequence: MEPGVRARSGAPQPASPVLWRARPAGGGGASSWLLLDGNSWLLCYGFLYLALYAQVSQSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLVAVLSGLIVPEVRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVASQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGAVSRGPLQRYGHSLALYQENIFMYGGRMETSDGNVTDELWVFNVRSQSWSTKTPTVLGHSQQYAVEGHSAHIMELDSRDVVMIVIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEVTKSIYVHGGYKALPGNKYGLVDDLYKYEVNTRTWTILKESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKTLPKPNLHRDVNRFGHSAVVINGSMYIFGGFSSVLLNDILVYKPPNCKAFRDEELCRNAGPGIKCVWNKNHCESWESGNTNNILRAKCPPKTAATDDRCYRYADCASCTANTNGCQWCDDKKCISASSNCSTSVRNYTKCHIRNEQICNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWNHVGDACLRINSSRESYDNAKLYCYNLSGNLASLTTSKEVEFVLDEIQKFTQQKVSPWVGLRKINISYWGWEDMSPFTNTSLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMADGLVCEKPVVSPNQNARPCKKPCSLRTSCANCTSSGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGYCIEGSSRGPMKLAGVHNSDVVLDTSLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGRQCQECMPGYYGDPTNGGQCTACTCGGHANVCHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTGGTISGEETPIVSKTNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTDFLRGPLEGAPKPIAIEPCAGNRAAVLTVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKPSDNKDKTSGVRNRKHLSTRQGTCV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
75	N-linked_Glycosylation	CFSGRCVNSTCLCDP CCCCCCCCCEEEECC	34.92	-
173	N-linked_Glycosylation	IVPEVRGNETVPEVV CCCCCCCCCCCCEEE	31.07	-
197	N-linked_Glycosylation	FFSDAAYNLTGFNIF HHHHHHCCCCCCEEE	26.80	-
379	N-linked_Glycosylation	RMETSDGNVTDELWV EEECCCCCCCCEEEE	38.21	-
703	N-linked_Glycosylation	NCSTSVRNYTKCHIR CCCHHHHHCCEEEEC	46.82	-
774	Phosphorylation	SYDNAKLYCYNLSGN CCCCCEEEEEECCCC	7.68	29233185
776	Phosphorylation	DNAKLYCYNLSGNLA CCCEEEEEECCCCEE	12.94	29233185
777	N-linked_Glycosylation	NAKLYCYNLSGNLAS CCEEEEEECCCCEEE	24.95	-
779	Phosphorylation	KLYCYNLSGNLASLT EEEEEECCCCEEECC	23.23	29233185
784	Phosphorylation	NLSGNLASLTTSKEV ECCCCEEECCCCCHH	29.43	29233185
786	Phosphorylation	SGNLASLTTSKEVEF CCCEEECCCCCHHHH	26.91	29233185
787	Phosphorylation	GNLASLTTSKEVEFV CCEEECCCCCHHHHH	42.99	29233185
897	N-linked_Glycosylation	SLRTSCANCTSSGME CCCCCCCCCCCCCCE	33.65	-
1156	N-linked_Glycosylation	ASNNFNLNITWSVGS CCCCCEEEEEEEECC	30.65	-
1329	Phosphorylation	FLCLPRGSSGAPPPG EEECCCCCCCCCCCC	27.21	25777480
1330	Phosphorylation	LCLPRGSSGAPPPGQ EECCCCCCCCCCCCH	41.62	25777480
1338	Phosphorylation	GAPPPGQSGLAIASA CCCCCCHHHHHHHHH	41.51	25777480
1344	Phosphorylation	QSGLAIASALIDISQ HHHHHHHHHHHHHHH	19.93	25777480
1350	Phosphorylation	ASALIDISQQKPSDN HHHHHHHHHCCCCCC	23.86	25777480
1355	Phosphorylation	DISQQKPSDNKDKTS HHHHCCCCCCCCCCC	61.93	25777480

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ATRN1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATRN1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATRN1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ATRN1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.