ATP23_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATP23_HUMAN
• UniProt AC: Q9Y6H3
• Protein Name: Mitochondrial inner membrane protease ATP23 homolog
• Gene Name: ATP23 {ECO:0000312|HGNC:HGNC:29452}
• Organism: Homo sapiens (Human).
• Sequence Length: 246
• Protein Sequence: MAGAPDERRRGPAAGEQLQQQHVSCQVFPERLAQGNPQQGFFSSFFTSNQKCQLRLLKTLETNPYVKLLLDAMKHSGCAVNKDRHFSCEDCNGNVSGGFDASTSQIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHFGLKQHHQTCVRDRATLSILAVRNISKEVAKKAVDEVFESCFNDHEPFGRIPHNKTYARYAHRDFENRDRYYSNI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
58	Ubiquitination	KCQLRLLKTLETNPY HHEEHHHHHHCCCHH	56.51	29967540
76	Phosphorylation	LLDAMKHSGCAVNKD HHHHHHHCCCCCCCC	30.01	24425749
203	Ubiquitination	ISKEVAKKAVDEVFE CCHHHHHHHHHHHHH	43.86	29967540
226	Ubiquitination	FGRIPHNKTYARYAH CCCCCCCCCCHHHCC	39.62	29967540
227	Phosphorylation	GRIPHNKTYARYAHR CCCCCCCCCHHHCCC	27.94	-
228	Phosphorylation	RIPHNKTYARYAHRD CCCCCCCCHHHCCCC	7.24	-
231	Phosphorylation	HNKTYARYAHRDFEN CCCCCHHHCCCCCCC	9.89	-
243	Phosphorylation	FENRDRYYSNI---- CCCCHHHCCCC----	8.99	22461510
244	Phosphorylation	ENRDRYYSNI----- CCCHHHCCCC-----	21.08	22461510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ATP23_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATP23_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATP23_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ATP23_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.