| UniProt ID | ATG9B_HUMAN | |
|---|---|---|
| UniProt AC | Q674R7 | |
| Protein Name | Autophagy-related protein 9B | |
| Gene Name | ATG9B | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 924 | |
| Subcellular Localization |
Cytoplasmic vesicle, autophagosome membrane Multi-pass membrane protein . Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistri |
|
| Protein Description | Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity).. | |
| Protein Sequence | MVSRMGWGGRRRRLGRWGDLGPGSVPLLPMPLPPPPPPSCRGPGGGRISIFSLSPAPHTRSSPSSFSPPTAGPPCSVLQGTGASQSCHSALPIPATPPTQAQPAMTPASASPSWGSHSTPPLAPATPTPSQQCPQDSPGLRVGPLIPEQDYERLEDCDPEGSQDSPIHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSKVTLSDAILPSAQCAERIRSSPLLVLLLVLAAGFWLVQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLALQRSGGLCVQPRPLTELDIHHRILRYTNYQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSDQRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLTVYDEDVLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYLPEEPGPGGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSAGQTEASLSQRAEDGKTELSLMRFSLAHPLWRPPGHSSKFLGHLWGRVQQDAAAWGATSARGPSTPGVLSNCTSPLPEAFLANLFVHPLLPPRDLSPTAPCPAAATASLLASISRIAQDPSSVSPGGTGGQKLAQLPELASAEMSLHVIYLHQLHQQQQQQEPWGEAAASILSRPCSSPSQPPSPDEEKPSWSSDGSSPASSPRQQWGTQKARNLFPGGFQVTTDTQKEPDRASCTD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 20 (in isoform 2) | Phosphorylation | - | 8.64 | 22210691 | |
| 21 (in isoform 2) | Phosphorylation | - | 29.30 | 22210691 | |
| 24 | Phosphorylation | WGDLGPGSVPLLPMP CCCCCCCCCCCCCCC | 24.56 | - | |
| 40 (in isoform 2) | Phosphorylation | - | 7.81 | 22210691 | |
| 185 | Phosphorylation | VPEGLRGSWHHIQNL CCCCCCCCHHHHHCH | 19.46 | 30631047 | |
| 703 | Ubiquitination | SQRAEDGKTELSLMR HHHHHCCCCHHHHHH | 51.66 | - | |
| 857 | Phosphorylation | PWGEAAASILSRPCS CHHHHHHHHHHCCCC | 21.24 | 24719451 | |
| 860 | Phosphorylation | EAAASILSRPCSSPS HHHHHHHHCCCCCCC | 32.29 | 24719451 | |
| 864 | Phosphorylation | SILSRPCSSPSQPPS HHHHCCCCCCCCCCC | 48.22 | 23663014 | |
| 865 | Phosphorylation | ILSRPCSSPSQPPSP HHHCCCCCCCCCCCC | 34.98 | 23663014 | |
| 867 | Phosphorylation | SRPCSSPSQPPSPDE HCCCCCCCCCCCCCC | 58.21 | 23663014 | |
| 871 | Phosphorylation | SSPSQPPSPDEEKPS CCCCCCCCCCCCCCC | 52.22 | 23663014 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ATG9B_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ATG9B_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ATG9B_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of ATG9B_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
