ATG22_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATG22_SCHPO
• UniProt AC: Q09812
• Protein Name: Autophagy-related protein 22
• Gene Name: atg22
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 529
• Subcellular Localization: Vacuole membrane ; Multi-pass membrane protein .
• Protein Description: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation..
• Protein Sequence: MNSPIQLHKKFSTTVWHVLSWILYAVGAGPTAIISMGVYVPLIVMKNAHDHGFLRTDHTIPCSLYPEEPCSLNIVGPLWIDVSSIVFAASAISTFLQMAMMVSLGVICDYGNNRRYILFSCVIIGSISGIILSWSPSSFLLGKIVFLILVDLNFIISQSCYDSFLPIFLRFYPITRGPITLESALQDETDDLDSYITNTTIDSSEEEPYLLEHSLILNESAPPADVEDEHKAKIAARLSSVGFGSFFGAAILFQIIFTPILYKTNNNPIILPITVTVCSCWWLILSTPLCTIVTLPVENHSSDAILTLLYNSVKESYHSFKHAMSISSIRLFLFSRLFINCGIQTSLSSAVIFGKARLNLSNFQLTLLGMGISSFALLGTVIIPYLTEYFQLNSLQVVMIISILLPMAPLYGLLGYIPGFENAGIRTSADVFRATLFFGFFLGGAHSYCRSVYAQLVPSGKETRFFALYALISQTGVLFSHISLTLISNYTSDLRAVYIFVIVVMTLPLSSLWIMYQHSKTPNLHRSSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MNSPIQLHKK -----CCCCCCHHHH	23.29	24763107
198	N-linked_Glycosylation	DLDSYITNTTIDSSE CHHHHHHCCCCCCCC	26.18	-
218	N-linked_Glycosylation	LEHSLILNESAPPAD EEEEEECCCCCCCCC	33.90	-
299	N-linked_Glycosylation	IVTLPVENHSSDAIL EEEEECCCCCHHHHH	40.34	-
359	N-linked_Glycosylation	IFGKARLNLSNFQLT HHCCHHCCCCCHHHH	35.55	-
489	N-linked_Glycosylation	ISLTLISNYTSDLRA HHHHHHHCCCCCHHH	36.79	-
527	Phosphorylation	KTPNLHRSSS----- CCCCCCCCCC-----	24.96	21712547
529	Phosphorylation	PNLHRSSS------- CCCCCCCC-------	45.55	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ATG22_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATG22_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATG22_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of ATG22_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.